SCHEMBL4610600

SCHEMBL4610600

Nc1ccc2[nH]c(=O)[nH]c(=O)c2c1

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 6/20 0.62
CA12 O43570 3/20 0.54
CA9 Q16790 3/20 0.54
KDM4E B2RXH2 2/20 0.53
AR P10275 1/20 0.49
NGFR P08138 1/20 0.49
ALDH1A1 P00352 1/20 0.46
HPGD P15428 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
PDE10A Q9Y233 1/20 0.45
MAPKAPK2 P49137 1/20 0.44
RPS6KA3 P51812 1/20 0.44
CSNK2A1 P68400 1/20 0.44
PLK3 Q9H4B4 1/20 0.44
PARG Q86W56 1/20 0.43
PDE3A Q14432 1/20 0.41
KIF11 P52732 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9862133 0.86 PARP1 (0.49) PARP1CA12CA9KDM4EAR
SCHEMBL5368114 0.84 PARP1 (0.67) PARP1CA12CA9KDM4EAR
SCHEMBL30586623 0.84 PARP1 (0.67) PARP1CA12CA9KDM4EAR
SCHEMBL92048 0.79 GAA (0.53) PARP1CA12CA9KDM4EAR
SCHEMBL29558701 0.79 GAA (0.53) PARP1CA12CA9KDM4EAR
SCHEMBL1230435 0.77 PARP1 (1.00) PARP1KDM4EALDH1A1PARG
Hydrochloric Acid SCHEMBL27948201 0.77 GAA (0.57) PARP1CA12CA9KDM4EAR
SCHEMBL5342370 0.77 PARP1 (0.58) PARP1CA12CA9KDM4EAR
Water SCHEMBL11163622 0.77 GAA (0.52) PARP1CA12CA9KDM4EAR
SCHEMBL182445 0.76 JAK2 (0.60) PARP1CA12CA9KDM4EAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120079352-A Preparation method and application of magnetic nano material for selectively adsorbing mercury ions 安康学院 2025-06-03 CN claimed
US-6548647-B2 Spraying coupling components in solution or suspension to collide in reactor chamber, then pressurizing to remove; useful for offset printing inks CLARIANT GMBH (DE) 2003-04-15 US claimed
US-20020055619-A1 Process for preparing azo colorants CLARIANT GMBH 2002-05-09 US claimed
EP-1195411-A1 Process for the preparation of azo colourants Clariant GmbH (DE) 2002-04-10 EP claimed
CN-120079352-A Preparation method and application of magnetic nano material for selectively adsorbing mercury ions 安康学院 2025-06-03 CN disclosed
EP-4306538-A2 PEPTIDE OLIGONUCLEOTIDE CONJUGATES Sarepta Therapeutics, Inc. (US) 2024-01-17 EP disclosed
CN-109776434-B 3-benzyl-6-acylamino-2, 4- (1H,3H) -quinazoline diketone derivative and synthesis method and application thereof 中南大学 2022-01-28 CN disclosed
US-10752640-B2 Compounds active towards bromodomains NUEVOLUTION A/S (DK) 2020-08-25 US disclosed
US-10752640-B2 Compounds active towards bromodomains NUEVOLUTION A/S (DK) 2020-08-25 US disclosed
US-20170349607-A1 COMPOUNDS ACTIVE TOWARDS BROMODOMAINS NUEVOLUTION A/S (DK) 2017-12-07 US disclosed
US-20170349607-A1 COMPOUNDS ACTIVE TOWARDS BROMODOMAINS NUEVOLUTION A/S (DK) 2017-12-07 US disclosed
EP-3173401-A1 PROCESS FOR THE SYNTHESIS OF ARYLDIAZONIUM SALTS USING NITROGEN OXIDES IN OXYGEN-CONTAINING GAS STREAMS, ESPECIALLY FROM INDUSTRIAL WASTE GASES Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) 2017-05-31 EP disclosed
EP-0585873-A1 Method of preparing disazo pigments HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-09 EP disclosed
EP-0518909-A1 WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE. HOECHST AG (DE) 1992-12-23 EP disclosed
EP-0316649-B1 WATER INSOLUBLE AZO COLOURING AGENTS, THEIR PREPARATION AND USE HOECHST AKTIENGESELLSCHAFT (DE) 1992-07-22 EP disclosed
WO-1991013941-A1 WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE HOECHST AKTIENGESELLSCHAFT (DE) 1991-09-19 WO disclosed
EP-0316649-A2 Water insoluble azo colouring agents, their preparation and use HOECHST AKTIENGESELLSCHAFT (DE) 1989-05-24 EP disclosed
EP-0000737-B1 MONOAZO PIGMENTS OF THE ACETOACETYLAMINO BENZIMIDAZOLONE SERIES, THEIR PREPARATION AND THEIR USE FOR COLOURING ORGANIC MATERIAL OF HIGH MOLECULAR WEIGHT CIBA-GEIGY AG (CH) 1981-04-29 EP disclosed
EP-0000737-A1 Monoazo pigments of the acetoacetylamino benzimidazolone series, their preparation and their use for colouring organic material of high molecular weight CIBA-GEIGY AG (CH) 1979-02-21 EP disclosed
US-4122117-A Indandione bis-azomethine pigments DAINIPPON INK & CHEMICALS, INC. (JP) 1978-10-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170349607-A1 COMPOUNDS ACTIVE TOWARDS BROMODOMAINS BRD4, BRD3, BRDT PARP1 50/4885CA12 4430/4885CA9 4490/4885
US-10752640-B2 Compounds active towards bromodomains BRD4, BRD3, BRDT PARP1 50/4885CA12 4430/4885CA9 4490/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.