SCHEMBL5368114

SCHEMBL5368114

Nc1ccc2c(=O)[nH]c(=O)[nH]c2c1

nearest known ligand 0.67

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 8/20 0.67
CA12 O43570 3/20 0.53
CA9 Q16790 3/20 0.53
KDM4E B2RXH2 2/20 0.53
AR P10275 2/20 0.49
ALDH1A1 P00352 1/20 0.46
HPGD P15428 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
KIF11 P52732 1/20 0.44
CDK4 P11802 1/20 0.44
CCND1 P24385 1/20 0.44
IMPDH2 P12268 1/20 0.39
TYMS P04818 1/20 0.39
TYMP P19971 1/20 0.38
GSK3B P49841 1/20 0.38
BACE1 P56817 1/20 0.38
TNKS2 Q9H2K2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30586623 1.00 PARP1 (0.67) PARP1CA12CA9KDM4EAR
SCHEMBL4610600 0.84 PARP1 (0.62) PARP1CA12CA9KDM4EAR
SCHEMBL10813479 0.80 PARP1 (1.00) PARP1CA12CA9KDM4EAR
SCHEMBL29558701 0.79 GAA (0.53) PARP1CA12CA9KDM4EAR
SCHEMBL92048 0.79 GAA (0.53) PARP1CA12CA9KDM4EAR
SCHEMBL6651281 0.77 PARP1 (0.79) PARP1KDM4EARALDH1A1CDK4
Water SCHEMBL11163622 0.77 GAA (0.52) PARP1CA12CA9KDM4EAR
Hydrochloric Acid SCHEMBL27948201 0.77 GAA (0.57) PARP1CA12CA9KDM4EAR
SCHEMBL5332607 0.77 PARP1 (0.62) PARP1CA12CA9KDM4EAR
SCHEMBL31312450 0.77 PARP1 (0.62) PARP1CA12CA9KDM4EAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116770379-A High corrosion resistant coating, preparation method, electrolyte and application thereof 聂正圆 2023-09-19 CN claimed
CN-116770379-A High corrosion resistant coating, preparation method, electrolyte and application thereof 聂正圆 2023-09-19 CN disclosed
CN-116770379-A High corrosion resistant coating, preparation method, electrolyte and application thereof 聂正圆 2023-09-19 CN disclosed
US-7455949-B2 Polymer for heat-sensitive lithographic printing plate precursor AGFA GRAPHICS, N.V. (BE) 2008-11-25 US disclosed
US-7455949-B2 Polymer for heat-sensitive lithographic printing plate precursor AGFA GRAPHICS, N.V. (BE) 2008-11-25 US disclosed
EP-1554324-B1 POLYMER FOR HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2008-05-28 EP disclosed
US-7262284-B2 Method for producing disazo pigments CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2007-08-28 US disclosed
US-20060167236-A1 Method for producing disazo pigments CLARIANT GMBH (DE) 2006-07-27 US disclosed
EP-1517962-A1 METHOD FOR PRODUCING DISAZO PIGMENTS Clariant GmbH (DE) 2005-03-30 EP disclosed
WO-2004000947-A1 METHOD FOR PRODUCING DISAZO PIGMENTS CLARIANT GMBH (DE) 2003-12-31 WO disclosed
EP-0675172-A2 Water-solable azo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-04 EP disclosed
EP-0518909-B1 WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE HOECHST AG (DE) 1994-05-25 EP disclosed
EP-0585873-A1 Method of preparing disazo pigments HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-09 EP disclosed
EP-0518909-A1 WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE. HOECHST AG (DE) 1992-12-23 EP disclosed
EP-0316649-B1 WATER INSOLUBLE AZO COLOURING AGENTS, THEIR PREPARATION AND USE HOECHST AKTIENGESELLSCHAFT (DE) 1992-07-22 EP disclosed
WO-1991013941-A1 WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE HOECHST AKTIENGESELLSCHAFT (DE) 1991-09-19 WO disclosed
US-5026831-A Water-insoluble disazo colorants having hetero-bicyclic methylene-active compounds as coupling component HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-25 US disclosed
EP-0316649-A2 Water insoluble azo colouring agents, their preparation and use HOECHST AKTIENGESELLSCHAFT (DE) 1989-05-24 EP disclosed
EP-0000737-B1 MONOAZO PIGMENTS OF THE ACETOACETYLAMINO BENZIMIDAZOLONE SERIES, THEIR PREPARATION AND THEIR USE FOR COLOURING ORGANIC MATERIAL OF HIGH MOLECULAR WEIGHT CIBA-GEIGY AG (CH) 1981-04-29 EP disclosed
EP-0000737-A1 Monoazo pigments of the acetoacetylamino benzimidazolone series, their preparation and their use for colouring organic material of high molecular weight CIBA-GEIGY AG (CH) 1979-02-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060167236-A1 Method for producing disazo pigments TYR, IPO4, CBR3 PARP1 1693/4885CA12 1138/4885CA9 1804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.