SCHEMBL461095

SCHEMBL461095

C=C(C(=O)O)C(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 9/20 0.48
NPSR1 Q6W5P4 2/20 0.44
CYP1A2 P05177 2/20 0.43
PTPN1 P18031 1/20 0.41
MAPT P10636 1/20 0.40
KMT2A Q03164 1/20 0.40
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
CYP2C19 P33261 2/20 0.39
HIF1A Q16665 1/20 0.39
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
HDAC9 Q9UKV0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10603215 0.84 KCNN4 (0.49) KCNN4NPSR1MAPTKMT2AALDH1A1
SCHEMBL3951407 0.82 KCNN4 (0.45) KCNN4NPSR1CYP1A2PTPN1MAPT
SCHEMBL5052734 0.82 KCNN4 (0.53) KCNN4NPSR1CYP1A2PTPN1MAPT
SCHEMBL3951414 0.81 KCNN4 (0.39) KCNN4NPSR1CYP1A2PTPN1ALDH1A1
SCHEMBL5838974 0.80 ALDH1A1 (0.41) KCNN4MAPTALDH1A1TSHRHDAC1
SCHEMBL9795924 0.80 KCNN4 (0.44) KCNN4NPSR1CYP1A2PTPN1MAPT
SCHEMBL1563521 0.79 CYP1A2 (0.41) KCNN4CYP1A2PTPN1MAPTKMT2A
SCHEMBL5071313 0.77 KMT2A (0.57) KCNN4CYP1A2PTPN1MAPTKMT2A
SCHEMBL9358927 0.77 CYP1A2 (0.45) KCNN4NPSR1CYP1A2PTPN1MAPT
SCHEMBL29099358 0.77 PTPN1 (0.48) KCNN4CYP1A2PTPN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8871315-B2 Triphenyl monomers suitable for microstructured optical films 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-10-28 US claimed
EP-0158357-B1 METHOD OF FORMING RESIST MICROPATTERN NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1991-02-27 EP claimed
EP-0204444-B1 BINDER FOR ANTI-FOULING PAINTS COURTAULDS COATINGS (HOLDINGS) LIMITED (GB) 1989-08-02 EP claimed
US-4634645-A FORMING RECESSED PATTERN WITH ENERGY BEAM NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1987-01-06 US claimed
EP-0158357-A2 Method of forming resist micropattern NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1985-10-16 EP claimed
WO-2019198630-A1 ANTIFOULING COATING COMPOSITION 日東化成株式会社 2019-10-17 WO disclosed
US-9885807-B2 Triphenyl monomers suitable for microstructured optical films 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-02-06 US disclosed
US-9383482-B2 Antireflective films comprising microstructured surface 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-07-05 US disclosed
US-20160109618-A1 TRIPHENYL MONOMERS SUITABLE FOR MICROSTRUCTURED OPTICAL FILMS 3M INNOVATIVE PROPERTIES CO (US) 2016-04-21 US disclosed
US-9221743-B2 Triphenyl monomers suitable for microstructured optical films 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-12-29 US disclosed
US-20150141692-A1 TRIPHENYL MONOMERS SUITABLE FOR MICROSTRUCTURED OPTICAL FILMS 3M INNOVATIVE PROPERTIES CO (US) 2015-05-21 US disclosed
US-8871315-B2 Triphenyl monomers suitable for microstructured optical films 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-10-28 US disclosed
WO-2010141345-A1 ANTIGLARE FILMS COMPRISING MICROSTRUCTURED SURFACE 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-12-09 WO disclosed
EP-2125914-A2 TRIPHENYL MONOMERS SUITABLE FOR MICROSTRUCTURED OPTICAL FILMS 3M Innovative Properties Company (US) 2009-12-02 EP disclosed
WO-2008112452-A2 TRIPHENYL MONOMERS SUITABLE FOR MICROSTRUCTURED OPTICAL FILMS 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-09-18 WO disclosed
US-6046791-A Polymer dispersed liquid crystal electro-optical device and method for manufacturing the same SEIKO EPSON CORPORATION (JP) 2000-04-04 US disclosed
EP-0821260-A1 POLYMER-DISPERSED LIQUID-CRYSTAL ELECTROOPTICAL DEVICE AND METHOD OF PRODUCTION THEREOF SEIKO EPSON CORPORATION (JP) 1998-01-28 EP disclosed
EP-0158357-B1 METHOD OF FORMING RESIST MICROPATTERN NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1991-02-27 EP disclosed
US-4634645-A FORMING RECESSED PATTERN WITH ENERGY BEAM NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1987-01-06 US disclosed
EP-0158357-A2 Method of forming resist micropattern NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1985-10-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150141692-A1 TRIPHENYL MONOMERS SUITABLE FOR MICROSTRUCTURED OPTICAL FILMS TRDMT1, TERB1, TIPARP KCNN4 3147/4885NPSR1 4692/4885CYP1A2 3493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.