Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4611812 | 0.86 | TDP1 (0.47) | KMT2ADRD2DRD4 | |
| SCHEMBL4611997 | 0.80 | L3MBTL1 (0.53) | SLC1A2TP53 | |
| SCHEMBL4611557 | 0.79 | SLC1A2 (0.59) | SLC1A2DRD2 | |
| SCHEMBL21835175 | 0.78 | KCNA5 (0.52) | — | |
| SCHEMBL4168265 | 0.77 | SLC6A3 (0.59) | DRD2DRD4 | |
| SCHEMBL4164304 | 0.77 | KDM4E (0.55) | KMT2A | |
| SCHEMBL4172177 | 0.77 | SLC1A2 (0.48) | SLC1A2DRD2DRD4 | |
| SCHEMBL31127634 | 0.76 | KCNA5 (0.55) | — | |
| Bromide SCHEMBL4171916 | 0.76 | SLC6A3 (0.58) | DRD2DRD4 | |
| SCHEMBL17865308 | 0.76 | SLC1A2 (0.56) | SLC1A2KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981849-A1 | HETEROCYCLIC COMPOUNDS | LEK Pharmaceuticals D.D. (SI) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007073935-A1 | HETEROCYCLIC COMPOUNDS | LEK PHARMACEUTICALS D.D. (SI) | 2007-07-05 | — | — | WO | disclosed |