Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4611623 | 0.86 | L3MBTL1 (0.56) | L3MBTL1 | |
| SCHEMBL4611557 | 0.80 | SLC1A2 (0.59) | LMNASLC1A2 | |
| SCHEMBL4164304 | 0.80 | KDM4E (0.55) | — | |
| SCHEMBL4611075 | 0.80 | SLC1A2 (0.48) | TP53SLC1A2 | |
| Bromide SCHEMBL4173363 | 0.79 | KDM4E (0.53) | — | |
| SCHEMBL4168265 | 0.78 | SLC6A3 (0.59) | — | |
| SCHEMBL4172177 | 0.78 | SLC1A2 (0.48) | L3MBTL1SLC1A2 | |
| Bromide SCHEMBL4171916 | 0.77 | SLC6A3 (0.58) | — | |
| SCHEMBL17865308 | 0.77 | SLC1A2 (0.56) | LMNATP53SLC1A2MAPT | |
| SCHEMBL4613070 | 0.77 | MC4R (0.53) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981849-A1 | HETEROCYCLIC COMPOUNDS | LEK Pharmaceuticals D.D. (SI) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007073935-A1 | HETEROCYCLIC COMPOUNDS | LEK PHARMACEUTICALS D.D. (SI) | 2007-07-05 | — | — | WO | disclosed |