Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | UBE2M | P61081 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4611203 | 1.00 | PTGS2 (0.44) | PTGS2MEN1KMT2APOLBSENP1 | |
| SCHEMBL4611459 | 0.87 | CYP3A4 (0.42) | MEN1KMT2ASENP1AOC3NR1H4 | |
| SCHEMBL4611463 | 0.87 | CYP3A4 (0.42) | MEN1KMT2ASENP1AOC3NR1H4 | |
| SCHEMBL2085860 | 0.84 | KDM4E (0.46) | LTB4R2AOC3NR1H4AKR1C2AKR1C3 | |
| SCHEMBL2085859 | 0.84 | KDM4E (0.46) | LTB4R2AOC3NR1H4AKR1C2AKR1C3 | |
| SCHEMBL2083354 | 0.82 | FFAR1 (0.50) | LTB4R2AOC3 | |
| SCHEMBL2086580 | 0.81 | NR1H4 (0.43) | NR1H4 | |
| SCHEMBL2086581 | 0.81 | NR1H4 (0.43) | NR1H4 | |
| SCHEMBL4217637 | 0.80 | SENP1 (0.41) | POLBSENP1LTB4R2AOC3KDR | |
| SCHEMBL4217628 | 0.80 | SENP1 (0.41) | POLBSENP1LTB4R2AOC3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781297-B1 | NOVEL BIAROMATIC COMPOUNDS THAT ACTIVATE PPAR TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2008-10-15 | — | — | EP | claimed |