Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.40 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4611459 | 1.00 | CYP3A4 (0.42) | CYP3A4CYP2C9AOC3SENP1NR1H4 | |
| SCHEMBL4611206 | 0.87 | PTGS2 (0.44) | CYP3A4CYP2C9AOC3SENP1NR1H4 | |
| SCHEMBL4611203 | 0.87 | PTGS2 (0.44) | CYP3A4CYP2C9AOC3SENP1NR1H4 | |
| SCHEMBL4215721 | 0.84 | PNPLA2 (0.43) | AOC3SENP1MEN1KMT2A | |
| SCHEMBL2085860 | 0.82 | KDM4E (0.46) | AOC3NR1H4ITGB1BCHE | |
| SCHEMBL2085859 | 0.82 | KDM4E (0.46) | AOC3NR1H4ITGB1BCHE | |
| SCHEMBL4213623 | 0.81 | KDR (0.42) | AOC3SENP1MEN1KMT2A | |
| SCHEMBL2083354 | 0.81 | FFAR1 (0.50) | AOC3ITGB1 | |
| SCHEMBL2087012 | 0.80 | AKR1B10 (0.45) | SENP1NR1H4BCHEACHE | |
| SCHEMBL2087010 | 0.80 | AKR1B10 (0.45) | SENP1NR1H4BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781297-B1 | NOVEL BIAROMATIC COMPOUNDS THAT ACTIVATE PPAR TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2008-10-15 | — | — | EP | claimed |