Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4609903 | 0.72 | SMN1; SMN2 (0.38) | HSD17B10ADRA1BADRA1DADRA1ALMNA | |
| SCHEMBL5715714 | 0.70 | ALDH1A1 (0.61) | KDM4EADRA1BHTR1AADRA1DADRA1A | |
| SCHEMBL5670386 | 0.70 | ADAM10 (0.43) | HSD17B10CXCR3ADRA1BHTR1AADRA1D | |
| SCHEMBL14924451 | 0.70 | HSD17B10 (0.66) | HSD17B10KDM4EGLAALDH1A1LMNA | |
| SCHEMBL6441668 | 0.69 | ALDH1A1 (0.65) | KDM4EADRA1BHTR1AADRA1DADRA1A | |
| SCHEMBL29891888 | 0.69 | ALDH1A1 (0.65) | KDM4EADRA1BHTR1AADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL29749177 | 0.69 | ALDH1A1 (0.65) | KDM4EADRA1BHTR1AADRA1DADRA1A | |
| SCHEMBL4610312 | 0.68 | HSD17B10 (0.43) | HSD17B10KDM4EGLAALDH1A1LMNA | |
| SCHEMBL14924038 | 0.68 | HSD17B10 (0.62) | HSD17B10KDM4EGLAALDH1A1LMNA | |
| SCHEMBL14566100 | 0.68 | ACACB (0.46) | ALDH1A1LMNASMN1; SMN2GRM5GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641771-B1 | HYDROXAMATE SULFONAMIDES AS CD23 SHEDDING INHIBITORS | UCB PHARMA SA (BE) | 2008-10-15 | — | — | EP | disclosed |