Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10012838 | 0.84 | ALDH1A1 (0.43) | MAPTALDH1A1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL5422875 | 0.77 | ALDH1A1 (0.39) | BRD4MAPTCES2CES1ALDH1A1 | |
| SCHEMBL295827 | 0.77 | ALDH1A1 (0.39) | BRD4MAPTCES2CES1ALDH1A1 | |
| SCHEMBL13241992 | 0.77 | ALDH1A1 (0.39) | BRD4MAPTCES2CES1ALDH1A1 | |
| SCHEMBL17735816 | 0.77 | ALDH1A1 (0.39) | BRD4MAPTCES2CES1ALDH1A1 | |
| SCHEMBL13136838 | 0.77 | ALDH1A1 (0.39) | BRD4MAPTCES2CES1ALDH1A1 | |
| SCHEMBL13242003 | 0.76 | CES2 (0.39) | MAPTNPSR1CES2CES1ALDH1A1 | |
| SCHEMBL6232784 | 0.76 | RAB9A (0.49) | MAPTALDH1A1LMNAMEN1MAPK1 | |
| SCHEMBL13241980 | 0.75 | ALDH1A1 (0.42) | MAPTCES2CES1ALDH1A1LMNA | |
| Ammonia Solution, Strong SCHEMBL5931927 | 0.75 | ALDH1A1 (0.38) | BRD4MAPTCES2CES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6046348-A | Silane compound, method for making the same, and electrophotographic photoreceptor | FUJI XEROX CO., LTD. (JP) | 2000-04-04 | — | — | US | disclosed |