Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAAO | P46952 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9249101 | 0.92 | HAAO (0.42) | HAAOALDH1A1CYP1A2HSD17B10KDM4E | |
| SCHEMBL195882 | 0.90 | CYP1A2 (0.44) | HAAOALDH1A1CYP1A2HSD17B10KDM4E | |
| Sulfuric Acid SCHEMBL4611666 | 0.89 | METAP2 (0.38) | HAAOALDH1A1METAP2CYP1A2HSD17B10 | |
| Ammonia Solution, Strong SCHEMBL28622226 | 0.88 | HAAO (0.42) | HAAOALDH1A1CYP1A2HSD17B10KDM4E | |
| SCHEMBL9408349 | 0.88 | HAAO (0.42) | HAAOALDH1A1CYP1A2HSD17B10KDM4E | |
| Water SCHEMBL27552128 | 0.88 | HAAO (0.42) | HAAOALDH1A1CYP1A2HSD17B10KDM4E | |
| Sulfuric Acid SCHEMBL4611664 | 0.87 | METAP2 (0.39) | HAAOALDH1A1METAP2CYP1A2HSD17B10 | |
| Cyclohexane SCHEMBL9558619 | 0.85 | HAAO (0.40) | HAAOALDH1A1CYP1A2HSD17B10KDM4E | |
| SCHEMBL27886205 | 0.81 | HAAO (0.38) | HAAOALDH1A1CYP1A2HSD17B10KDM4E | |
| SCHEMBL6574602 | 0.80 | RXRB (0.38) | HAAOALDH1A1CYP1A2HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1217024-B1 | Process for the preparation of spinnable and dyeable polyester resins | MONTEFIBRE SPA (IT) | 2008-03-12 | — | — | EP | disclosed |
| EP-1217024-A1 | Process for the preparation of spinnable and dyeable polyester resins | Montefibre S.p.A. (IT) | 2002-06-26 | — | — | EP | disclosed |