Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4611695 | 1.00 | F7 (0.42) | F7F3PPARGPPARACNR1 | |
| SCHEMBL7110020 | 0.94 | PPARG (0.47) | F7F3PPARGPPARACNR1 | |
| SCHEMBL7115034 | 0.87 | TAS1R3 (0.46) | PPARGPPARACNR1CNR2FFAR1 | |
| SCHEMBL31509214 | 0.87 | TAS1R3 (0.46) | PPARGPPARACNR1CNR2FFAR1 | |
| SCHEMBL454223 | 0.85 | F7 (0.44) | F7F3PPARGPPARACNR1 | |
| SCHEMBL454225 | 0.85 | F7 (0.44) | F7F3PPARGPPARACNR1 | |
| SCHEMBL8150368 | 0.79 | PPARG (0.49) | F7F3PPARGPPARAPTPN1 | |
| SCHEMBL8150365 | 0.79 | PPARG (0.49) | F7F3PPARGPPARAPTPN1 | |
| SCHEMBL14681838 | 0.78 | PPARG (0.51) | F7F3PPARGPPARAPTPN1 | |
| SCHEMBL9231091 | 0.76 | PPARG (0.46) | F7F3PPARGPPARACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879860-A2 | 1,4-DIPHENYL-3-HYDROXYALKYL-2-AZETIDINONE DERIVATIVES FOR TREATING HYPERCHOLESTROLEMIA | Microbia Inc. (US) | 2008-01-23 | — | — | EP | disclosed |
| EP-1877373-A2 | BIPHENYLAZETIDINONE CHOLESTEROL ABSORPTION INHIBITORS | Microbia, Inc. (US) | 2008-01-16 | — | — | EP | disclosed |
| WO-2006122186-A2 | 1,4-DIPHENYL-3-HYDROXYALKYL-2-AZETIDINONE DERIVATIVES FOR TREATING HYPERCHOLESTROLEMIA | MICROBIA, INC. (US) | 2006-11-16 | — | — | WO | disclosed |
| WO-2006121861-A2 | BIPHENYLAZETIDINONE CHOLESTEROL ABSORPTION INHIBITORS | MICROBIA, INC. (US) | 2006-11-16 | — | — | WO | disclosed |
| US-20040176336-A1 | Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium | RODRIGUEZ GUSTAVO C (US) | 2004-09-09 | — | — | US | disclosed |
| EP-1357193-A1 | Preparation of pyrazines | SOCIETE DES PRODUITS NESTLE S.A. (CH) | 2003-10-29 | — | — | EP | disclosed |