SCHEMBL4611904

SCHEMBL4611904

c1ccc2sc(SNN3CCOCC3)nc2c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.64
HSD17B10 Q99714 3/20 0.64
HPGD P15428 3/20 0.64
ALOX15 P16050 2/20 0.64
PKM P14618 2/20 0.64
KDM4E B2RXH2 1/20 0.64
MAPK1 P28482 2/20 0.54
SMN1; SMN2 Q16637 4/20 0.54
NPC1 O15118 3/20 0.54
RAB9A P51151 3/20 0.54
LMNA P02545 1/20 0.52
TDP1 Q9NUW8 2/20 0.49
ADRA2A P08913 1/20 0.49
FBP1 P09467 1/20 0.49
ADORA3 P0DMS8 1/20 0.49
DRD2 P14416 1/20 0.49
ADRA2B P18089 1/20 0.49
ADRA2C P18825 1/20 0.49
DRD1 P21728 1/20 0.49
MC5R P33032 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Mercaptobenzothiazole SCHEMBL10987039 0.93 ALDH1A1 (0.56) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL11453732 0.87 ALDH1A1 (0.56) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL11455872 0.86 ALDH1A1 (0.58) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL11464463 0.86 ALDH1A1 (0.58) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL3246368 0.82 MAPT (0.57) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL6915262 0.81 ALDH1A1 (0.69) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL7937072 0.80 ALDH1A1 (0.56) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL28167550 0.79 ALDH1A1 (0.66) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL29404281 0.78 ALDH1A1 (1.00) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL79658 0.78 ALDH1A1 (1.00) ALDH1A1HSD17B10HPGDALOX15PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023094230-A1 FOOTWEAR SOLE MADE OF RUBBER COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2023-06-01 WO claimed
US-20200385559-A1 HIGH MODULUS RUBBER COMPOSITION COMPRISING AN EFFECTIVE SULFUR CROSSLINKING SYSTEM COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2020-12-10 US claimed
EP-3717561-A1 HIGH-MODULUS RUBBER COMPOSITION COMPRIISNG A VULCANISATION ULTRA-ACCELERATOR Compagnie Générale des Etablissements Michelin (FR) 2020-10-07 EP claimed
CN-111433047-A High modulus rubber compositions comprising an effective sulfur crosslinking system 米其林集团总公司 2020-07-17 CN claimed
CN-111433270-A High modulus rubber compositions comprising vulcanization ultra-accelerators 米其林集团总公司 2020-07-17 CN claimed
US-4229325-A VULCANIZABLE COPOLYMERS OR TERPOLYMERS, A SULFUR DONOR, A DELAYED ACTION ACCELERATOR; GEL-FREE EXXON RESEARCH & ENGINEERING CO. (US) 1980-10-21 US claimed
US-4215022-A GEL-FREE EXXON RESEARCH & ENGINEERING CO. (US) 1980-07-29 US claimed
US-4153584-A High molecular weight high unsaturation C4 -C10 isoolefin conjugated diolefin copolymers and multipolymers containing methylcyclopentadiene EXXON RESEARCH & ENGINEERING CO. (US) 1979-05-08 US claimed
US-12497499-B2 Polymer composition production method ENEOS MATERIALS CORPORATION (JP) 2025-12-16 US disclosed
EP-4071208-B1 POLYMER COMPOSITION MANUFACTURING METHOD ENEOS MAT CORPORATION (JP) 2025-09-10 EP disclosed
US-20250019527-A1 RUBBER MIXTURE COMPRISING A RAPID VULCANIZATION ACCELERATOR COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2025-01-16 US disclosed
US-12071545-B2 High-modulus rubber composition comprising a vulcanization ultra-accelerator COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2024-08-27 US disclosed
US-12060489-B2 Tire provided with an inner layer made from at least an isoprene elastomer, a reinforcing resin and a metal salt COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2024-08-13 US disclosed
US-20240043662-A1 RUBBER COMPOSITION WITH IMPROVED RESISTANCE TO MECHANICAL STRESS COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2024-02-08 US disclosed
US-4215022-A GEL-FREE EXXON RESEARCH & ENGINEERING CO. (US) 1980-07-29 US disclosed
US-4182873-A AMINATION OF MERCAPTO THIAZOLE OR DISULFIDE RHONE-POULENC S.A. (FR) 1980-01-08 US disclosed
US-4153773-A HIGH MOLECULAR WEIGHT EXXON RESEARCH & ENGINEERING CO. (US) 1979-05-08 US disclosed
US-4153584-A High molecular weight high unsaturation C4 -C10 isoolefin conjugated diolefin copolymers and multipolymers containing methylcyclopentadiene EXXON RESEARCH & ENGINEERING CO. (US) 1979-05-08 US disclosed
US-4151343-A High unsaturation butyl rubbers EXXON RESEARCH & ENGINEERING CO. (US) 1979-04-24 US disclosed
US-4139695-A High molecular weight high unsaturation C4-C10 isoolefin conjugated diolefin copolymers and multipolymers containing methylcyclopentadiene EXXON RESEARCH & ENGINEERING CO. (US) 1979-02-13 US disclosed