Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL846609 | 0.97 | MEN1 (0.33) | MEN1ALDH1A1KMT2ACA1CA2 | |
| SCHEMBL4612542 | 0.95 | MEN1 (0.33) | MEN1ALDH1A1KMT2ACA1CA2 | |
| Hydrochloric Acid SCHEMBL6465548 | 0.90 | MEN1 (0.35) | MEN1ALDH1A1KMT2A | |
| Bromide SCHEMBL8034463 | 0.74 | ALDH1A1 (0.33) | MEN1ALDH1A1KMT2ACA1CA2 | |
| Hydrochloric Acid SCHEMBL3190099 | 0.72 | CHRNB2 (0.35) | — | |
| Hydrochloric Acid SCHEMBL6142328 | 0.71 | — | — | |
| SCHEMBL1025201 | 0.71 | ALDH1A1 (0.36) | MEN1ALDH1A1KMT2ACA1CA2 | |
| Hydrochloric Acid SCHEMBL4634124 | 0.71 | ALDH1A1 (0.33) | MEN1ALDH1A1KMT2ACA1CA2 | |
| Bromide SCHEMBL616105 | 0.71 | HTR2A (0.39) | MEN1KMT2AHTR2C | |
| Hydrochloric Acid SCHEMBL2777393 | 0.69 | ALDH1A1 (0.30) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575123-B2 | Ethylene copolymer composition | MITSUI CHEMICALS INC (JP) | 2008-02-13 | — | — | EP | disclosed |
| US-6894120-B2 | Ethylene copolymer composition | MITSUI CHEMICALS, INC. (JP) | 2005-05-17 | — | — | US | disclosed |
| US-20040210004-A1 | Ethylene copolymer composition | TAKAHASHI MAMORU (JP) | 2004-10-21 | — | — | US | disclosed |
| US-6774190-B1 | LOW DENSITY POLYETHYLENE OBTAINED BY HIGH-PRESSURE FREE RADICAL POLYMERIZATION; HEAT RESISTANCE, STABILITY, MOLDABILITY, AND TRANSPARENCY; ANTI-BLOCKING RESISTANCE | MITSUI CHEMICALS, INC. (JP) | 2004-08-10 | — | — | US | disclosed |
| US-20030092845-A1 | Ethylene copolymer composition | TAKAHASHI MAMORU (JP) | 2003-05-15 | — | — | US | disclosed |
| US-20020165322-A1 | Ethylene copolymer composition | TAKAHASHI MAMORU (JP) | 2002-11-07 | — | — | US | disclosed |
| US-20020143126-A1 | Ethylene resin injection molded articles | TAKAHASHI MAMORU (JP) | 2002-10-03 | — | — | US | disclosed |
| US-6319961-B1 | ETHYLENE/ALPHA-OLEFIN COPOLYMER; DENSITY IS 0.880-0.940 G/CM3; MELT FLOW RATE AT 190 DEGREES C. UNDER A 2.16 KG LOAD IS 0.1-20 G/10 MIN | MITSUI CHEMICALS INC (JP) | 2001-11-20 | — | — | US | disclosed |
| EP-0575123-B1 | Ethylene copolymer composition | MITSUI CHEMICALS INC (JP) | 2000-08-30 | — | — | EP | disclosed |
| US-5674945-A | Ethylene copolymer composition | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-07 | — | — | US | disclosed |
| EP-0587365-B1 | Ethylene copolymer composition | MITSUI PETROCHEMICAL IND (JP) | 1997-04-23 | — | — | EP | disclosed |
| US-5594071-A | HEAT RESISTANCE, MOLDABILITY | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0587365-A2 | Ethylene copolymer composition | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1994-03-16 | — | — | EP | disclosed |
| EP-0575123-A2 | Ethylene copolymer composition | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1993-12-22 | — | — | EP | disclosed |