Hydrochloric Acid

Hydrochloric Acid

SCHEMBL3190099

C1=CC([Zr+2]2(C3C=Cc4c(-c5ccccc5)cccc43)CC2)c2cccc(-c3ccccc3)c21.[Cl-].[Cl-]

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.35
CHRNA4 P43681 1/20 0.35
ADRA2A P08913 3/20 0.32
ADRA2B P18089 2/20 0.32
ADRA2C P18825 2/20 0.32
ADRA1D P25100 1/20 0.31
ADRA1A P35348 1/20 0.31
BRD4 O60885 1/20 0.31
PARP10 Q53GL7 1/20 0.30
PARP11 Q9NR21 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL846609 0.76 MEN1 (0.33)
Hydrochloric Acid SCHEMBL6460888 0.74
2-Phenylphenol SCHEMBL7125528 0.74
Hydrochloric Acid SCHEMBL4088340 0.73 CHRNB2 (0.35) CHRNB2CHRNA4ADRA2AADRA2BADRA2C
Hydrochloric Acid SCHEMBL3685419 0.73 CHRNB2 (0.35) CHRNB2CHRNA4ADRA2AADRA2BADRA2C
Hydrochloric Acid SCHEMBL4089006 0.73 CHRNB2 (0.35) CHRNB2CHRNA4ADRA2AADRA2BADRA2C
Hydrochloric Acid SCHEMBL5872685 0.73 CHRNB2 (0.36) CHRNB2CHRNA4ADRA2AADRA2BADRA2C
Hydrochloric Acid SCHEMBL5872699 0.73 CHRNB2 (0.33) CHRNB2CHRNA4ADRA2AADRA2BADRA2C
Hydrochloric Acid SCHEMBL8426993 0.72 CHRNB2 (0.34) CHRNB2CHRNA4ADRA2AADRA2BADRA2C
Bromide SCHEMBL4611928 0.72 MEN1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2093268-B1 PRESSURE-SENSITIVE ADHESIVE SHEET NITTO DENKO CORP (JP) 2015-03-25 EP disclosed
EP-1780009-B1 LAYERED PRODUCT JAPAN POLYETHYLENE CORP (JP) 2013-10-30 EP disclosed
US-7767312-B2 Layered product JAPAN POLYETHYLENE CORPORATION (JP) 2010-08-03 US disclosed
US-20100028671-A1 PRESSURE-SENSITIVE ADHESIVE SHEET NITTO DENKO CORPROATION 2010-02-04 US disclosed
US-20090290004-A1 INK RESERVOIR CANON KABUSHIKI KAISHA (JP) 2009-11-26 US disclosed
EP-2123459-A2 Ink reservoir Canon Kabushiki Kaisha (JP) 2009-11-25 EP disclosed
EP-2093268-A1 PRESSURE-SENSITIVE ADHESIVE SHEET Nitto Denko Corporation (JP) 2009-08-26 EP disclosed
US-7341794-B2 Laminated film JAPAN POLYPROPYLENE CORPORATION (JP) 2008-03-11 US disclosed
US-20080051518-A1 Layered Product JAPAN POLYETHYLENE CORPORATION (JP) 2008-02-28 US disclosed
EP-1780009-A1 LAYERED PRODUCT Japan Polyethylene Corporation (JP) 2007-05-02 EP disclosed
US-6825280-B1 RIGIDITY, NONWARPING, NONBLEEDING, ANTISTATIC AGENTS, WEATHERPROOF, IMPACT STRENGTH; OXIDATION AND HEAT RESISTANCE JAPAN POLYCHEM CORPORATION (JP) 2004-11-30 US disclosed
US-20040216846-A1 Laminated film JAPAN POLYPROPYLENE CORPORATION (JP) 2004-11-04 US disclosed
EP-0962474-B1 Propylene block copolymer and resin composition JAPAN POLYCHEM CORP (JP) 2004-04-07 EP disclosed
US-6469100-B2 COORDINATION CATALYST JAPAN POLYCHEM CORPORATION (JP) 2002-10-22 US disclosed
US-20010014719-A1 PROPYLENE BLOCK COPOLYMER AND RESIN COMPOSITION JAPAN POLYCHEM CORPORATION (JP) 2001-08-16 US disclosed
EP-1002814-A1 PROPYLENE BLOCK COPOLYMER AND PROPYLENE RESIN COMPOSITION Japan Polychem Corporation (JP) 2000-05-24 EP disclosed
EP-0962474-A1 Propylene block copolymer and resin composition Japan Polychem Corporation (JP) 1999-12-08 EP disclosed
US-5942459-A ALUMOXANE-FREE MIXTURE OF TRANSITION METAL METALLOCENE, ORGANOALUMINUM COMPOUND, BORIC ACID-CONTAINING POWDER MITSUBISHI CHEMICAL CORPORATION (JP) 1999-08-24 US disclosed
EP-0728773-B1 Catalysts for olefin polymerization and a process for preparing olefin polymers therewith MITSUBISHI CHEM CORP (JP) 1998-11-04 EP disclosed
EP-0728773-A1 Catalysts for olefin polymerization and a process for preparing olefin polymers therewith MITSUBISHI CHEMICAL CORPORATION (JP) 1996-08-28 EP disclosed