Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.83 |
| ▸ | HTR2A | P28223 | 6/20 | 0.47 |
| ▸ | HTR2B | P41595 | 3/20 | 0.47 |
| ▸ | DNM2 | P50570 | 4/20 | 0.43 |
| ▸ | PRKCA | P17252 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
| ▸ | PRKCH | P24723 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 2/20 | 0.41 |
| ▸ | PRKACG | P22612 | 2/20 | 0.41 |
| ▸ | PRKACB | P22694 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4651322 | 0.83 | HTR2C (0.65) | HTR2CHTR2AHTR2B | |
| SCHEMBL29359237 | 0.81 | HTR2C (0.81) | HTR2CHTR2AHTR2BHTR6 | |
| SCHEMBL4652431 | 0.79 | HTR2C (0.69) | HTR2CHTR2AHTR6 | |
| SCHEMBL4329033 | 0.79 | HTR2C (0.73) | HTR2CHTR2AHTR2BHTR6PIM1 | |
| SCHEMBL3245076 | 0.77 | HTR2C (0.66) | HTR2CHTR2AHTR6 | |
| SCHEMBL27587633 | 0.76 | HTR2C (0.56) | HTR2CHTR6 | |
| SCHEMBL29751560 | 0.75 | HTR2C (0.63) | HTR2CHTR2AHTR6 | |
| SCHEMBL4323537 | 0.75 | HTR2C (0.63) | HTR2CHTR2AHTR6 | |
| SCHEMBL2038502 | 0.75 | HTR2C (0.63) | HTR2CHTR6 | |
| SCHEMBL30517485 | 0.75 | HTR2C (0.63) | HTR2CHTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1002520-B1 | Composition for oxidative dying of keratinous fibres and dying process therewith | OREAL (FR) | 2008-10-29 | — | — | EP | claimed |
| US-6890362-B2 | Oxidation dyeing composition for keratinous fibers and dyeing method using same | L'OREAL, S.A. (FR) | 2005-05-10 | — | — | US | claimed |
| EP-0988021-B1 | KERATIN FIBRE OXIDATION DYEING COMPOSITION AND DYEING METHOD USING SAME | OREAL (FR) | 2003-11-12 | — | — | EP | claimed |
| US-20030009835-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | L'OREAL S.A. (FR) | 2003-01-16 | — | — | US | claimed |
| US-6395042-B1 | OXIDATION BASE, HETEROCYCLIC COUPLERS FOR OXIDATION COLOR DYE | L'ORÉAL (FR) | 2002-05-28 | — | — | US | claimed |
| EP-1181005-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2002-02-27 | — | — | EP | claimed |
| WO-2001066071-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2001-09-13 | — | — | WO | claimed |
| CN-1259039-A | Keratin fibre oxidation dyeing composition and dyeing method using same | OREAL (FR) | 2000-07-05 | — | — | CN | claimed |
| CN-1254552-A | Ceratin-fibre composition for oxidation dying and method for dying with solid composition | OREAL (FR) | 2000-05-31 | — | — | CN | claimed |
| EP-1002520-A1 | Composition for oxidative dying of keratinous fibres and dying process therewith | L'OREAL (FR) | 2000-05-24 | — | — | EP | claimed |
| EP-0988021-A1 | KERATIN FIBRE OXIDATION DYEING COMPOSITION AND DYEING METHOD USING SAME | L'OREAL (FR) | 2000-03-29 | — | — | EP | claimed |
| US-5869692-A | COUPLER FOR OXIDATION COLOR DYEING OF HAIR | L'OREAL (FR) | 1999-02-09 | — | — | US | claimed |
| WO-1998055083-A1 | KERATIN FIBRE OXIDATION DYEING COMPOSITION AND DYEING METHOD USING SAME | L'OREAL (FR) | 1998-12-10 | — | — | WO | claimed |
| EP-0754681-B1 | N-substituted 4-hydroxyindole derivatives and compositions for dyeing keratinous fibers containing them | OREAL (FR) | 1998-03-04 | — | — | EP | claimed |
| US-5704948-A | Compositions for dyeing keratinous fibers and keratinous fiber dyeing processes with derivatives of 4-hydroxyindole and oxidation bases | L'OREAL (FR) | 1998-01-06 | — | — | US | claimed |
| WO-1997003049-A1 | N-SUBSTITUTED 4-HYDROXYINDOLE DERIVATIVES AND KERATIN FIBRE DYEING COMPOSITIONS CONTAINING SAME | L'OREAL (FR) | 1997-01-30 | — | — | WO | claimed |
| EP-0754681-A1 | N-substituted 4-hydroxy-indole derivatives and compositions for dyeing keratinous fibers containing them | L'OREAL (FR) | 1997-01-22 | — | — | EP | claimed |
| EP-1002520-B1 | Composition for oxidative dying of keratinous fibres and dying process therewith | OREAL (FR) | 2008-10-29 | — | — | EP | disclosed |
| WO-1997003049-A1 | N-SUBSTITUTED 4-HYDROXYINDOLE DERIVATIVES AND KERATIN FIBRE DYEING COMPOSITIONS CONTAINING SAME | L'OREAL (FR) | 1997-01-30 | — | — | WO | disclosed |
| EP-0754681-A1 | N-substituted 4-hydroxy-indole derivatives and compositions for dyeing keratinous fibers containing them | L'OREAL (FR) | 1997-01-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030009835-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | KRT18, PPOX, NDUFB5 | HTR2C 3775/4885HTR2A 3862/4885HTR2B 3141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.