SCHEMBL461236

SCHEMBL461236

CCc1cnc(N2CCC(Oc3cc[nH]c(=S)c3)CC2)nc1

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 18/20 0.53
ACACB O00763 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2333333 0.88 GPR119 (0.57) GPR119ACACB
SCHEMBL1550376 0.79 GPR119 (0.58) GPR119ACACB
SCHEMBL461030 0.79 SCD (0.45) GPR119
SCHEMBL3178150 0.78 GPR119 (0.54) GPR119ACACB
SCHEMBL8515468 0.77 GPR119 (0.53) GPR119ACACB
SCHEMBL8513552 0.75 GPR119 (0.51) GPR119ACACB
SCHEMBL3342687 0.74 GPR119 (0.52) GPR119ACACB
SCHEMBL27855620 0.73 AOC3 (0.51) GPR119
SCHEMBL2330910 0.73 GPR119 (0.53) GPR119ACACB
SCHEMBL3341593 0.73 GPR119 (0.51) GPR119ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012011707-A2 SUBSTITUTED PYRIDINONE DERIVATIVES AND METHODS FOR MANUFACTURING THE SAME HYUNDAI PHARM CO., LTD. (KR) 2012-01-26 WO disclosed