Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.61 |
| ▸ | PPARG | P37231 | 7/20 | 0.61 |
| ▸ | PPARD | Q03181 | 7/20 | 0.61 |
| ▸ | PPARA | Q07869 | 7/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.61 |
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.61 |
| ▸ | FABP4 | P15090 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TLR2 | O60603 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.61 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | PDE4A | P27815 | 1/20 | 0.61 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Palmitic Acid SCHEMBL1815959 | 1.00 | GPR84 (0.61) | GPR84PPARGPPARDPPARAHDAC11 | |
| Myristic Acid SCHEMBL3299115 | 1.00 | GPR84 (0.61) | GPR84PPARGPPARDPPARAHDAC11 | |
| Hexanoate SCHEMBL2098722 | 0.98 | AKR1B1 (0.59) | GPR84PPARGPPARDPPARAHDAC11 | |
| Valeric Acid SCHEMBL29098873 | 0.93 | AKR1B1 (0.50) | GPR84PPARGPPARDPPARAHDAC11 | |
| Oleic Acid SCHEMBL28630252 | 0.91 | PPARG (0.68) | PPARGPPARDPPARATSHRPTPN1 | |
| Azelaic Acid SCHEMBL28918234 | 0.91 | TSHR (0.52) | GPR84PPARGPPARDPPARAHDAC11 | |
| Adipic Acid SCHEMBL29427201 | 0.89 | LMNA (0.50) | GPR84PPARGPPARDPPARATSHR | |
| Adipic Acid SCHEMBL906129 | 0.89 | LMNA (0.50) | GPR84PPARGPPARDPPARATSHR | |
| Undecanoate SCHEMBL28399891 | 0.86 | GPR84 (0.57) | GPR84PPARGPPARDPPARAHDAC11 | |
| Sebacic Acid SCHEMBL29286911 | 0.85 | GPR84 (0.50) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113041164-A | Application of succinimide stearate in preparation of anti-friction skin care masking liquid and anti-friction skin care masking liquid containing succinimide stearate | 广州武州制药有限公司 | 2021-06-29 | — | — | CN | claimed |
| CN-107531994-B | Method for preparing graft copolymer excipient with excellent peptide and protein binding property | 药明公司 | 2020-12-01 | — | — | CN | claimed |
| CN-110284580-A | It is a kind of for handling the integrated pump station of the anti-siltation of industrial wastewater | 贝德科技有限公司 | 2019-09-27 | — | — | CN | claimed |
| CN-113502153-B | Non-aromatic luminous micromolecule/SiO 2 Hybrid fluorescent nano material and preparation method and application thereof | 哈尔滨工程大学 | 2023-02-14 | — | — | CN | disclosed |
| CN-113502153-A | Non-aromatic luminous micromolecule/SiO2Hybrid fluorescent nano material and preparation method and application thereof | 哈尔滨工程大学 | 2021-10-15 | — | — | CN | disclosed |
| CN-113041164-A | Application of succinimide stearate in preparation of anti-friction skin care masking liquid and anti-friction skin care masking liquid containing succinimide stearate | 广州武州制药有限公司 | 2021-06-29 | — | — | CN | disclosed |
| CN-107531994-B | Method for preparing graft copolymer excipient with excellent peptide and protein binding property | 药明公司 | 2020-12-01 | — | — | CN | disclosed |
| CN-110284580-A | It is a kind of for handling the integrated pump station of the anti-siltation of industrial wastewater | 贝德科技有限公司 | 2019-09-27 | — | — | CN | disclosed |
| CN-103980148-B | Stearoyl amino acid salts and its preparation method and application | 上海交通大学医学院 | 2016-09-14 | — | — | CN | disclosed |
| CN-103980148-A | Stearoyl amino acid salt and preparation method and application thereof | SHANGHAI JIAOTONG UNIV SCHOOL MEDICINE | 2014-08-13 | — | — | CN | disclosed |
| EP-1421092-A4 | NEUTRAL GLYCOSPHINGOLIPIDS AND GLYCOSYL-SPHINGOSINES AND METHODS FOR ISOLATING THE SAME | NEOSE TECHNOLOGIES INC (US) | 2008-02-20 | — | — | EP | disclosed |
| US-6958325-B2 | Cationic polysaccharide compositions | EFRAT BIOPOLYMERS LIMITED (IL) | 2005-10-25 | — | — | US | disclosed |
| US-20050032742-A1 | Chemo-enzymatic synthesis of sialylated oligosaccharides | SENEB BIOSCIENCES, INC. | 2005-02-10 | — | — | US | disclosed |
| EP-1425408-A4 | CHEMO-ENZYMATIC SYNTHESIS OF SIALYLATED OLIGOSACCHARIDES | NEOSE TECHNOLOGIES INC (US) | 2004-11-10 | — | — | EP | disclosed |
| EP-1425408-A2 | CHEMO-ENZYMATIC SYNTHESIS OF SIALYLATED OLIGOSACCHARIDES | Neose Technologies, Inc. (US) | 2004-06-09 | — | — | EP | disclosed |
| EP-1421092-A1 | NEUTRAL GLYCOSPHINGOLIPIDS AND GLYCOSYL-SPHINGOSINES AND METHODS FOR ISOLATING THE SAME | Neose Technologies, Inc. (US) | 2004-05-26 | — | — | EP | disclosed |
| WO-2003016469-A2 | CHEMO-ENZYMATIC SYNTHESIS OF SIALYLATED OLIGOSACCHARIDES | NEOSE TECHNOLOGIES, INC. (US) | 2003-02-27 | — | — | WO | disclosed |
| WO-2003011879-A1 | NEUTRAL GLYCOSPHINGOLIPIDS AND GLYCOSYL-SPHINGOSINES AND METHODS FOR ISOLATING THE SAME | NEOSE TECHNOLOGIES, INC. (US) | 2003-02-13 | — | — | WO | disclosed |
| US-20020146826-A1 | Biodegradabel polysaccharide derivative for use in human therapeutic and diagnostics | POLYGENE LTD. | 2002-10-10 | — | — | US | disclosed |
| EP-1222926-A1 | Cationic polysaccharide compositions | Polygene Ltd. (IL) | 2002-07-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020146826-A1 | Biodegradabel polysaccharide derivative for use in human therapeutic and diagnostics | ALG1, CD44, CHIT1 | GPR84 716/4885PPARG 4622/4885PPARD 2859/4885 |
| US-20050032742-A1 | Chemo-enzymatic synthesis of sialylated oligosaccharides | CERS2, UGCG, NEU1 | GPR84 1140/4885PPARG 3476/4885PPARD 3222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.