SCHEMBL6694549

SCHEMBL6694549

Ic1cc2cc3ccccc3cc2c(I)c1I

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 2/20 0.38
ALDH1A1 P00352 7/20 0.36
HSD17B10 Q99714 4/20 0.36
HIF1A Q16665 2/20 0.36
CYP1B1 Q16678 1/20 0.36
NQO1 P15559 1/20 0.35
KDM4E B2RXH2 3/20 0.34
GAA P10253 2/20 0.34
F10 P00742 1/20 0.34
C1R P00736 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
CYP3A4 P08684 1/20 0.33
ALOX15 P16050 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
HBB P68871 1/20 0.33
MAPT P10636 2/20 0.32
GLA P06280 2/20 0.32
HPGD P15428 2/20 0.32
ACHE P22303 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5638671 0.81 ALDH1A1 (0.44) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL28604593 0.78 ALDH1A1 (0.43) ALDH1A1HSD17B10HIF1ACYP1B1NQO1
SCHEMBL4612665 0.77 ALDH1A1 (0.46) ALDH1A1HSD17B10HIF1ACYP1B1NQO1
SCHEMBL9612411 0.77 GRIN2D (0.50) ALDH1A1HSD17B10HIF1ACYP1B1NQO1
SCHEMBL30548751 0.74 CYP2A6 (0.47) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL14800228 0.74 CYP2A6 (0.47) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL15511865 0.72 ALDH1A1 (0.43) ALDH1A1HSD17B10HIF1ACYP1B1NQO1
SCHEMBL31108395 0.71 ALDH1A1 (0.50) ALDH1A1HSD17B10HIF1ACYP1B1NQO1
SCHEMBL4614015 0.71 ALDH1A1 (0.50) ALDH1A1HSD17B10HIF1ACYP1B1NQO1
Anthracene SCHEMBL28787108 0.71 ALDH1A1 (0.53) ALDH1A1HSD17B10HIF1ACYP1B1NQO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166043-A Electrolyte for sulfur-based magnesium battery 富士胶片和光纯药株式会社 2021-07-23 CN disclosed
US-20040197484-A1 Coating liquid for forming insulating film and method for producing insulating film SUMITOMO CHEMICAL COMPANY, LIMITED 2004-10-07 US disclosed