Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 9/20 | 0.57 |
| ▸ | CTSB | P07858 | 7/20 | 0.57 |
| ▸ | CTSS | P25774 | 7/20 | 0.57 |
| ▸ | CTSK | P43235 | 9/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4700585 | 0.83 | CTSL (0.58) | CTSLCTSBCTSSCTSK | |
| SCHEMBL4703540 | 0.74 | CTSL (0.69) | CTSLCTSBCTSSCTSK | |
| SCHEMBL27627210 | 0.73 | CTSL (0.57) | CTSLCTSBCTSSCTSK | |
| SCHEMBL6182715 | 0.73 | CTSL (1.00) | CTSLCTSBCTSSCTSK | |
| SCHEMBL4615386 | 0.73 | CTSK (1.00) | CTSLCTSBCTSK | |
| SCHEMBL4615378 | 0.73 | CTSK (1.00) | CTSLCTSBCTSK | |
| SCHEMBL4615384 | 0.73 | CTSK (1.00) | CTSLCTSBCTSK | |
| SCHEMBL1710445 | 0.72 | MAOA (0.43) | CTSLCTSBCTSSCTSK | |
| SCHEMBL1710546 | 0.70 | MAOA (0.44) | CTSK | |
| SCHEMBL4702168 | 0.66 | CTSK (0.49) | CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446115-B1 | CYANOALKYLAMINO DERIVATIVES AS PROTEASE INHIBITORS | MERCK FROSST CANADA LTD (CA) | 2008-02-27 | — | — | EP | claimed |