Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA3 | P07451 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA6 | P23280 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL332031 | 0.85 | KEAP1 (0.46) | KEAP1SMN1; SMN2SIGMAR1ALOX15CYP2D6 | |
| SCHEMBL15336923 | 0.81 | KEAP1 (0.39) | KEAP1SMN1; SMN2SIGMAR1CYP2D6 | |
| SCHEMBL1616800 | 0.80 | — | — | |
| SCHEMBL101501 | 0.80 | KEAP1 (0.67) | KEAP1SMN1; SMN2SIGMAR1ALOX15CYP2D6 | |
| Hydrochloric Acid SCHEMBL3673979 | 0.78 | KEAP1 (0.64) | KEAP1SMN1; SMN2SIGMAR1ALOX15CYP2D6 | |
| SCHEMBL15329386 | 0.78 | KEAP1 (0.64) | KEAP1SMN1; SMN2SIGMAR1ALOX15CYP2D6 | |
| SCHEMBL4801737 | 0.77 | KEAP1 (0.40) | KEAP1SMN1; SMN2SIGMAR1CYP2D6 | |
| SCHEMBL13876470 | 0.75 | SMN1; SMN2 (0.61) | KEAP1SMN1; SMN2SIGMAR1ALOX15CYP2D6 | |
| SCHEMBL4559690 | 0.75 | ALOX15 (0.77) | KEAP1SMN1; SMN2SIGMAR1ALOX15CYP2D6 | |
| SCHEMBL291327 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7082335-A | — | — | None | — | — | JP | disclosed |
| US-11046872-B2 | Two-component hot melt adhesive, solidified product, and method for controlling cross-linking time | TOYOTA BOSHOKU KABUSHIKI KAISHA (JP) | 2021-06-29 | — | — | US | disclosed |
| US-20200172772-A1 | TWO-COMPONENT HOT MELT ADHESIVE, SOLIDIFIED PRODUCT, AND METHOD FOR CONTROLLING CROSS-LINKING TIME | TOYOTA BOSHOKU KABUSHIKI KAISHA (JP) | 2020-06-04 | — | — | US | disclosed |
| CN-107148434-A | Low emission polyurethane foams made with isocyanate-reactive amine crystals | 赢创德固赛有限公司 | 2017-09-08 | — | — | CN | disclosed |
| CN-106810661-A | There is the delayed action catalyst of the polyurethane system stability containing halogen foaming agent for improving | 气体产品与化学公司 | 2017-06-09 | — | — | CN | disclosed |
| EP-1742978-B1 | METHOD FOR THE PRODUCTION OF POLYURETHANE FOAM MATERIALS | BASF SE (DE) | 2008-10-29 | — | — | EP | disclosed |
| US-20070254973-A1 | Method for the Production of Polyurethane Foam Materials | BASF AKTIENGESELLSCHAFT (DE) | 2007-11-01 | — | — | US | disclosed |
| US-20060058409-A1 | Method for producing rigid polyurethane foams by means of graft polyhydric alcohols | BASF AKTIENGESELLSCHAFT (DE) | 2006-03-16 | — | — | US | disclosed |
| JP-H0782335-A | CATALYST FOR PRODUCTION OF RIGID POLYURETHANE FOAM | TOSOH CORP | 1995-03-28 | — | — | JP | disclosed |
| JP-H00782335-A | — | — | 0001-01-01 | — | — | JP | disclosed |