Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4614142 | 0.77 | KEAP1 (0.52) | KEAP1SMN1; SMN2SIGMAR1CYP2D6 | |
| SCHEMBL332031 | 0.75 | KEAP1 (0.46) | KEAP1SMN1; SMN2SIGMAR1CYP2D6HSD17B10 | |
| SCHEMBL1616800 | 0.66 | — | — | |
| SCHEMBL101501 | 0.66 | KEAP1 (0.67) | KEAP1SMN1; SMN2SIGMAR1CYP2D6HSD17B10 | |
| SCHEMBL17433050 | 0.65 | KEAP1 (0.46) | KEAP1SMN1; SMN2SIGMAR1CYP2D6HSD17B10 | |
| SCHEMBL3966764 | 0.65 | GNAI3 (0.59) | KEAP1SMN1; SMN2SIGMAR1CYP2D6GNAI3 | |
| SCHEMBL9801323 | 0.64 | KEAP1 (0.41) | KEAP1SMN1; SMN2SIGMAR1CYP2D6HSD17B10 | |
| Hydrochloric Acid SCHEMBL3673979 | 0.64 | KEAP1 (0.64) | KEAP1SMN1; SMN2SIGMAR1CYP2D6 | |
| SCHEMBL15329386 | 0.64 | KEAP1 (0.64) | KEAP1SMN1; SMN2SIGMAR1CYP2D6HSD17B10 | |
| SCHEMBL18762872 | 0.64 | SMN1; SMN2 (0.41) | KEAP1SMN1; SMN2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1127086-B2 | IMPROVED CELLULAR PLASTIC MATERIAL | URETHANE SOY SYSTEMS CO (US) | 2008-01-09 | — | — | EP | claimed |