Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.64 |
| ▸ | PPARG | P37231 | 10/20 | 0.59 |
| ▸ | PPARD | Q03181 | 10/20 | 0.59 |
| ▸ | PPARA | Q07869 | 10/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | LSS | P48449 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4614555 | 0.90 | MAPK14 (0.64) | MAPK14PPARGPPARDPPARAHTR2C | |
| SCHEMBL4616068 | 0.87 | MMP13 (0.57) | MAPK14 | |
| SCHEMBL5416553 | 0.86 | PPARG (0.63) | MAPK14PPARGPPARDPPARA | |
| SCHEMBL4615231 | 0.84 | PPARA (0.73) | MAPK14PPARGPPARDPPARA | |
| SCHEMBL4616353 | 0.84 | PPARD (0.64) | MAPK14PPARGPPARDPPARA | |
| SCHEMBL5420067 | 0.84 | PPARG (0.85) | MAPK14PPARGPPARDPPARA | |
| SCHEMBL26625404 | 0.82 | MMP13 (0.66) | MAPK14LSS | |
| SCHEMBL31060682 | 0.78 | MAPK14 (1.00) | MAPK14PPARGPPARDPPARALSS | |
| SCHEMBL26625342 | 0.77 | HDAC1 (0.63) | MAPK14LSS | |
| SCHEMBL4035947 | 0.77 | RAB9A (0.65) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697304-B1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2008-02-20 | — | — | EP | disclosed |