Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESPL1 | Q14674 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | S100A4 | P26447 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4615179 | 0.94 | ESPL1 (0.47) | ESPL1ACHEALDH1A1TSHRMAPT | |
| Hydrochloric Acid SCHEMBL4614659 | 0.93 | ESPL1 (0.49) | ESPL1ACHEALDH1A1TSHRMAPT | |
| Bromide SCHEMBL4614053 | 0.93 | ESPL1 (0.46) | ESPL1ACHEALDH1A1TSHRMAPT | |
| Sulfuric Acid SCHEMBL4614640 | 0.90 | ESPL1 (0.43) | ESPL1ACHEALDH1A1TSHRMAPT | |
| Sulfuric Acid SCHEMBL4614646 | 0.87 | MAPT (0.42) | ESPL1ACHEALDH1A1TSHRMAPT | |
| SCHEMBL7740556 | 0.83 | ACHE (0.41) | ESPL1ACHEALDH1A1TSHRMAPT | |
| Iodide SCHEMBL29419509 | 0.81 | TSHR (0.43) | ESPL1ACHEALDH1A1TSHRMAPT | |
| Iodide SCHEMBL28708116 | 0.81 | TSHR (0.43) | ESPL1ACHEALDH1A1TSHRMAPT | |
| SCHEMBL10623250 | 0.75 | ESPL1 (0.40) | ESPL1ALDH1A1TSHRMAPTTDP1 | |
| SCHEMBL10082444 | 0.75 | MAPT (0.61) | ESPL1ACHEALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1699427-B1 | AGENT AND METHOD FOR OXIDATIVELY DYING KERATIN FIBERS | WELLA AG (DE) | 2008-02-27 | — | — | EP | claimed |
| US-7244278-B2 | Agent and method for oxidative coloring of keratin fibers | WELLA AG (DE) | 2007-07-17 | — | — | US | claimed |
| US-20070067927-A1 | Agent and method for oxidative coloring of keratin fibers | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2007-03-29 | — | — | US | claimed |
| US-7244278-B2 | Agent and method for oxidative coloring of keratin fibers | WELLA AG (DE) | 2007-07-17 | — | — | US | disclosed |
| US-20070067927-A1 | Agent and method for oxidative coloring of keratin fibers | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070067927-A1 | Agent and method for oxidative coloring of keratin fibers | KRT18, KIT, AOC1 | ESPL1 2311/4885ACHE 489/4885ALDH1A1 137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.