Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | LDLR | P01130 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2353921 | 0.78 | LDLR (0.61) | ALDH1A1KMT2AMEN1NPSR1NPC1 | |
| SCHEMBL4615147 | 0.77 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1TDP1HTT | |
| SCHEMBL29788091 | 0.77 | FFAR2 (0.51) | ALDH1A1KMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL2040639 | 0.77 | FFAR2 (0.51) | ALDH1A1KMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL11731614 | 0.76 | ALDH1A1 (0.70) | ALDH1A1KMT2AMEN1TDP1HTT | |
| SCHEMBL11730422 | 0.74 | ALDH1A1 (0.67) | ALDH1A1KMT2AMEN1TDP1HTT | |
| SCHEMBL3559504 | 0.71 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1TDP1HTT | |
| SCHEMBL6783138 | 0.71 | LDLR (0.86) | ALDH1A1KMT2AMEN1HTTNPSR1 | |
| SCHEMBL5648458 | 0.70 | SMN1; SMN2 (0.53) | ALDH1A1KMT2AMEN1HTTNPC1 | |
| SCHEMBL4945184 | 0.69 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1TDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940786-A1 | BIPHENYL DERIVATIVES AND THEIR USE IN TREATING HEPATITIS C | Arrow Therapeutics Limited (GB) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007031791-A1 | BIPHENYL DERIVATIVES AND THEIR USE IN TREATING HEPATITIS C | ARROW THERAPEUTICS LIMITED (GB) | 2007-03-22 | — | — | WO | disclosed |