Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2040639 | 1.00 | FFAR2 (0.51) | FFAR2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL29788136 | 0.87 | KDM4E (0.55) | FFAR2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL3640507 | 0.86 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDCSNK2A2CSNK2A1 | |
| SCHEMBL29788225 | 0.79 | NR3C1 (0.56) | NPC1RAB9AALDH1A1GAAMEN1 | |
| SCHEMBL2034374 | 0.79 | NR3C1 (0.56) | NPC1RAB9AALDH1A1GAAMEN1 | |
| SCHEMBL14635732 | 0.77 | NR3C1 (0.46) | KDM4EALDH1A1HPGDGAAMEN1 | |
| SCHEMBL30159253 | 0.77 | NR1H4 (0.51) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL2951399 | 0.77 | NR1H4 (0.51) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL4615151 | 0.77 | ALDH1A1 (0.66) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL14817806 | 0.76 | ALDH1A1 (0.65) | KDM4ENPC1RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773249-A | Compounds, pharmaceutical compositions and methods for treating inflammatory diseases | 艾匹克治疗公司 | 2022-07-22 | — | — | CN | disclosed |