Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 6/20 | 0.38 |
| ▸ | MET | P08581 | 18/20 | 0.38 |
| ▸ | KDR | P35968 | 12/20 | 0.37 |
| ▸ | IGF1R | P08069 | 9/20 | 0.37 |
| ▸ | MERTK | Q12866 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2158304 | 0.96 | AXL (0.39) | AXLMETKDRIGF1RMERTK | |
| SCHEMBL2151233 | 0.89 | PLAU (0.39) | AXLMETKDRIGF1RMERTK | |
| SCHEMBL374249 | 0.86 | AXL (0.42) | AXLMETKDRIGF1RMERTK | |
| SCHEMBL377027 | 0.85 | MET (0.40) | AXLMETKDRMERTK | |
| SCHEMBL3422130 | 0.84 | MET (0.52) | AXLMETKDRIGF1RMERTK | |
| SCHEMBL3418984 | 0.83 | AXL (0.42) | AXLMETKDRIGF1RMERTK | |
| SCHEMBL3421428 | 0.83 | MET (0.35) | AXLMETKDRIGF1RMERTK | |
| SCHEMBL2151613 | 0.83 | MET (0.36) | AXLMETKDRIGF1RMERTK | |
| SCHEMBL3419332 | 0.81 | MET (0.35) | AXLMETKDRIGF1RMERTK | |
| SCHEMBL374396 | 0.79 | MET (0.46) | AXLMETKDRMERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408300-B1 | AMINO ESTER DERIVATIVES, SALTS THEREOF AND METHODS OF USE | SUNSHINE LAKE PHARMA CO LTD (CN) | 2016-05-11 | — | — | EP | disclosed |
| US-8232294-B2 | Amino ester derivatives, sailts thereof and methods of use | Xi, Ning (US) | 2012-07-31 | — | — | US | disclosed |
| EP-2408300-A1 | AMINO ESTER DERIVATIVES, SALTS THEREOF AND METHODS OF USE | Sunshine Lake Pharma Co., Ltd (CN) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010111063-A1 | AMINO ESTER DERIVATIVES, SALTS THEREOF AND METHODS OF USE | XI NING (US) | 2010-09-30 | — | — | WO | disclosed |
| US-20100239576-A1 | AMINO ESTER DERIVATIVES, SAILTS THEREOF AND METHODS OF USE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100239576-A1 | AMINO ESTER DERIVATIVES, SAILTS THEREOF AND METHODS OF USE | SRC, BCAT1, BCAT2 | AXL 373/4885MET 185/4885KDR 958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.