Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31591913 | 0.69 | RAPGEF4 (0.45) | — | |
| SCHEMBL36967 | 0.69 | — | — | |
| SCHEMBL996566 | 0.69 | GSK3A (0.33) | — | |
| SCHEMBL6676619 | 0.69 | HTR6 (0.48) | PTGS2 | |
| SCHEMBL28120461 | 0.68 | XIAP (0.31) | — | |
| Hydrochloric Acid SCHEMBL5322363 | 0.67 | — | — | |
| Benzene SCHEMBL28483360 | 0.65 | GSK3B (0.31) | — | |
| Benzene SCHEMBL27617257 | 0.65 | GSK3B (0.31) | — | |
| SCHEMBL5030857 | 0.64 | — | — | |
| SCHEMBL9587810 | 0.62 | GSK3B (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879564-A2 | COMPOUNDS TO TREAT AMYLOIDOSIS AND PREVENT DEATH OF BETA-CELLS IN TYPE 2 DIABETES MELLITUS | Astrum Therapeutics Pty, Ltd. (AU) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006110477-A2 | COMPOUNDS TO TREAT AMYLOIDOSIS AND PREVENT DEATH OF BETA-CELLS IN TYPE 2 DIABETES MELLITUS | ASTRUM THERAPEUTICS PTY. LTD. (AU) | 2006-10-19 | — | — | WO | disclosed |