SCHEMBL6676619

SCHEMBL6676619

O=C1C=C(S(=O)(=O)c2ccccc2)C(=O)N1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 2/20 0.48
AKR1B1 P15121 1/20 0.40
PSIP1 O75475 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
CASP3 P42574 1/20 0.36
CASP2 P42575 1/20 0.36
CASP7 P55210 1/20 0.36
CASP6 P55212 1/20 0.36
CASP8 Q14790 1/20 0.36
ALDH1A1 P00352 2/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA3 P07451 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
CA5A P35218 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Phenylsulfonyl)Benzene SCHEMBL10700102 0.81 HTR6 (0.50) HTR6AKR1B1MEN1KMT2AALDH1A1
SCHEMBL29727868 0.78 CA2 (0.44) KMT2ACASP3TDP1CA12CA1
SCHEMBL30946720 0.71 HTR6 (0.56) HTR6AKR1B1MEN1KMT2ACASP3
(Phenylsulfonyl)Benzene SCHEMBL9597781 0.71 HTR6 (0.64) HTR6AKR1B1MEN1KMT2AALDH1A1
(Phenylsulfonyl)Benzene SCHEMBL28184987 0.71 HTR6 (0.64) HTR6AKR1B1MEN1KMT2AALDH1A1
SCHEMBL3377876 0.69 MAPT (0.43) HTR6MEN1KMT2AALDH1A1TDP1
SCHEMBL22144487 0.69 PSIP1 (0.42) PSIP1KMT2AALDH1A1HSD17B10TDP1
SCHEMBL4615219 0.69 PTGS2 (0.32) PTGS2
(Phenylsulfonyl)Benzene SCHEMBL29450723 0.68 HTR6 (1.00) HTR6PSIP1ALDH1A1HSD17B10TDP1
(Phenylsulfonyl)Benzene SCHEMBL13735236 0.68 HTR6 (1.00) HTR6PSIP1ALDH1A1HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1468332-A1 PHOTOSENSITIVE COMPOSITION AND PHOTOSENSITIVE PLANOGRAPHIC PRINTING PLATE Kodak Polychrome Graphics Company Ltd. (US) 2004-10-20 EP disclosed
WO-2003062924-A1 PHOTOSENSITIVE COMPOSITION AND PHOTOSENSITIVE PLANOGRAPHIC PRINTING PLATE KODAK POLYCHROME GRAPHICS COMPANY LTD. (US) 2003-07-31 WO disclosed
EP-0574934-A1 Method for forming a patterned polyimide coating film on a substrate E.I. DU PONT DE NEMOURS & COMPANY INCORPORATED (US) 1993-12-22 EP disclosed
EP-0057018-B1 PHOTO-CURABLE EPOXY RESIN COMPOSITION KABUSHIKI KAISHA TOSHIBA (JP) 1985-06-05 EP disclosed