Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1S | P09871 | 6/20 | 0.44 |
| ▸ | PLAU | P00749 | 5/20 | 0.44 |
| ▸ | SREBF2 | Q12772 | 3/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | TKT | P29401 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6319677 | 0.86 | SRC (0.46) | SRCZAP70SYKTKTNPC1 | |
| SCHEMBL1821128 | 0.81 | ALDH1A1 (0.54) | C1SPLAUSREBF2LOXL2NPC1 | |
| SCHEMBL1818589 | 0.73 | RAB9A (0.55) | C1SPLAUSREBF2GFERNPC1 | |
| SCHEMBL260421 | 0.73 | LMNA (0.54) | NPC1MAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL263873 | 0.71 | SRC (0.46) | SRCZAP70SYKNPC1MAPT | |
| SCHEMBL1823007 | 0.71 | KDM4E (0.53) | SREBF2LOXL2NPC1MAPTRAB9A | |
| SCHEMBL1206446 | 0.70 | ALDH1A1 (0.61) | C1SPLAUSREBF2NPC1MAPT | |
| SCHEMBL1820141 | 0.70 | C1S (0.49) | C1SNPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL207818 | 0.68 | CYP19A1 (0.64) | NPC1MAPTRAB9AALDH1A1KDM4E | |
| SCHEMBL207728 | 0.68 | CYP19A1 (0.59) | GFERNPC1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351945-B1 | NOVEL 1,4-DIAMINO-2-(THIAZOL-2-YL)BENZENE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2008-01-23 | — | — | EP | disclosed |