SCHEMBL4615276

SCHEMBL4615276

COc1ccc(C(C)CCN)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.54
TAAR1 Q96RJ0 1/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C19 P33261 1/20 0.47
SLC6A4 P31645 1/20 0.46
GAA P10253 1/20 0.45
MAPT P10636 1/20 0.45
AOC3 Q16853 3/20 0.44
MAOB P27338 2/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA12 O43570 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
ABCB11 O95342 1/20 0.43
ACHE P22303 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4615417 0.98 ALDH1A1 (0.53) ALDH1A1TAAR1MEN1KMT2ACYP1A2
SCHEMBL6984086 0.89 ALDH1A1 (0.47) ALDH1A1TAAR1MEN1KMT2ACYP1A2
SCHEMBL6183991 0.83 TAAR1 (0.56) ALDH1A1TAAR1CYP1A2CYP2D6CYP2C19
SCHEMBL1989112 0.83 TAAR1 (0.56) ALDH1A1TAAR1CYP1A2CYP2D6CYP2C19
SCHEMBL4014153 0.83 TAAR1 (0.56) ALDH1A1TAAR1CYP1A2CYP2D6CYP2C19
SCHEMBL1586430 0.82 CYP1A2 (0.46) ALDH1A1MEN1KMT2ACYP1A2CYP2D6
SCHEMBL5947827 0.82 KMT2A (0.65) ALDH1A1TAAR1MEN1KMT2ACYP1A2
Hydrochloric Acid SCHEMBL5877324 0.82 TAAR1 (0.54) ALDH1A1TAAR1CYP1A2CYP2D6CYP2C19
SCHEMBL10052129 0.82 ALDH1A1 (0.50) ALDH1A1CYP1A2CYP2D6CYP2C19SLC6A4
SCHEMBL11947569 0.81 RIPK1 (0.61) ALDH1A1CYP1A2CYP2D6CYP2C19SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016077240-A2 ANTI-HCMV COMPOSITIONS AND METHODS FORGE LIFE SCIENCE, LLC (US) 2016-05-19 WO disclosed
EP-1879562-A2 PHENOL DERIVATIVES AND THEIR USE TO MODULATE PKB ACTIVITY Imperial Innovations Limited (GB) 2008-01-23 EP disclosed
WO-2006097744-A2 PHENOL DERIVATIVES AND THEIR USE TO MODULATE PKB ACTIVITY IMPERIAL INNOVATIONS LIMITED (GB) 2006-09-21 WO disclosed
WO-2006017406-A1 CYANOAMIDINE P2X7 ANTAGONISTS FOR THE TREATMENT OF PAIN ABBOTT LABORATORIES (US) 2006-02-16 WO disclosed
WO-2004056823-A1 PYRAZOLO[3,4-b]PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS GLAXO GROUP LIMITED (GB) 2004-07-08 WO disclosed
US-5028256-A Metolachlor and an acylamide compound, for maize or sorghum CIBA-GEIGY CORPORATION (US) 1991-07-02 US disclosed
US-4897109-A ACYLAMINE DERIVATIVE CIBA-GEIGY CORPORATION (US) 1990-01-30 US disclosed
EP-0163607-B1 MEANS FOR THE PROTECTION OF CULTURE PLANTS AGAINST THE PHYTOTOXIC ACTION OF CHLORACETANILIDE HERBICIDES CIBA-GEIGY AG (CH) 1989-11-08 EP disclosed
EP-0163607-A2 Means for the protection of culture plants against the phytotoxic action of chloracetanilide herbicides CIBA-GEIGY AG (CH) 1985-12-04 EP disclosed