SCHEMBL6984086

SCHEMBL6984086

COc1ccc(C(C)CCCN)cc1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
SLC7A5 Q01650 1/20 0.46
TAAR1 Q96RJ0 1/20 0.46
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C19 P33261 1/20 0.44
SLC6A4 P31645 1/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
KIF11 P52732 1/20 0.42
KCNH2 Q12809 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
AOC3 Q16853 3/20 0.42
MAOB P27338 1/20 0.42
ABCB11 O95342 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
ACHE P22303 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4615276 0.89 ALDH1A1 (0.54) ALDH1A1TAAR1CYP1A2CYP2D6CYP2C19
Hydrochloric Acid SCHEMBL4615417 0.87 ALDH1A1 (0.53) ALDH1A1TAAR1CYP1A2CYP2D6CYP2C19
SCHEMBL1586468 0.83 MMP13 (0.49) ALDH1A1CYP1A2CYP2D6CYP2C19GAA
SCHEMBL29657187 0.83 MMP13 (0.49) ALDH1A1CYP1A2CYP2D6CYP2C19GAA
SCHEMBL1587369 0.81 ABCB11 (0.49) ALDH1A1CYP1A2CYP2D6CYP2C19GAA
SCHEMBL29657138 0.81 ALDH1A1 (0.46) ALDH1A1GAAMAPTABCB11CA1
SCHEMBL6183991 0.80 TAAR1 (0.56) ALDH1A1TAAR1CYP1A2CYP2D6CYP2C19
SCHEMBL4014153 0.80 TAAR1 (0.56) ALDH1A1TAAR1CYP1A2CYP2D6CYP2C19
SCHEMBL1989112 0.80 TAAR1 (0.56) ALDH1A1TAAR1CYP1A2CYP2D6CYP2C19
SCHEMBL8903433 0.80 ABCB11 (0.47) ALDH1A1CYP1A2CYP2D6CYP2C19GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1289965-A1 SUBSTITUTED 1-AMINOALKYL-LACTAMS AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS F. HOFFMANN-LA ROCHE AG (CH) 2003-03-12 EP disclosed
WO-2001090081-A1 SUBSTITUTED 1-AMINOALKYL-LACTAMS AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS F. HOFFMANN-LA ROCHE AG (CH) 2001-11-29 WO disclosed