SCHEMBL4615602

SCHEMBL4615602

CCC(C=Cc1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
CYP1A2 P05177 2/20 0.47
LMNA P02545 2/20 0.42
HTR2A P28223 3/20 0.40
RELA Q04206 1/20 0.40
MAOB P27338 1/20 0.39
CYP3A4 P08684 1/20 0.39
THPO P40225 1/20 0.39
HIF1A Q16665 1/20 0.39
MTOR P42345 1/20 0.39
RAB9A P51151 1/20 0.39
PAM P19021 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
KDM4E B2RXH2 1/20 0.38
GMNN O75496 1/20 0.38
ALDH1A1 P00352 1/20 0.38
BLM P54132 1/20 0.38
PMP22 Q01453 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4615601 1.00 MEN1 (0.47) MEN1KMT2ACYP1A2LMNAHTR2A
SCHEMBL6547644 0.89 MEN1 (0.43) MEN1KMT2ACYP1A2HTR2ARELA
SCHEMBL6546314 0.89 CYP3A4 (0.41) MEN1KMT2ACYP1A2LMNARELA
SCHEMBL11676685 0.85 CYP1A2 (0.44) MEN1KMT2ACYP1A2HTR2ARELA
SCHEMBL11676687 0.85 CYP1A2 (0.44) MEN1KMT2ACYP1A2HTR2ARELA
SCHEMBL10631059 0.79 TRPA1 (0.46) CYP1A2HTR2ATDP1
SCHEMBL10631053 0.79 TRPA1 (0.46) CYP1A2HTR2ATDP1
SCHEMBL14910835 0.79 LMNA (0.45) MEN1KMT2ALMNAHTR2ARELA
SCHEMBL5855883 0.79 LMNA (0.45) MEN1KMT2ALMNAHTR2ATDP1
SCHEMBL5855884 0.79 LMNA (0.45) MEN1KMT2ALMNAHTR2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1288235-B1 Agents for the improvement of the vulcanisation behaviour in the preparation of grafted or crosslinked polymers and filled resins EVONIK DEGUSSA GMBH (DE) 2008-02-20 EP claimed
US-6864323-B2 Composition for improving scorch conditions in the preparation of grafted and/or crosslinked polymers and of filled plastics DEGUSSA AG (DE) 2005-03-08 US claimed
US-20030114604-A1 Composition for improving scorch conditions in the preparation of grafted and/or crosslinked polymers and of filled plastics DEGUSA AG (DE) 2003-06-19 US claimed
CN-118871436-A Synthesis of pyrazolyl derivatives useful as anticancer agents 诺华股份有限公司 2024-10-29 CN disclosed
US-6864323-B2 Composition for improving scorch conditions in the preparation of grafted and/or crosslinked polymers and of filled plastics DEGUSSA AG (DE) 2005-03-08 US disclosed
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-20030114604-A1 Composition for improving scorch conditions in the preparation of grafted and/or crosslinked polymers and of filled plastics DEGUSA AG (DE) 2003-06-19 US disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed
US-4994539-A Ethylene-unsaturated aromatic copolymer NIPPON PETROCHEMICALS CO., LTD. (JP) 1991-02-19 US disclosed
EP-0180771-B1 METHOD FOR IMPROVING IMPULSE BREAKDOWN STRENGTH OF ELECTRICALLY INSULATING MATERIALS Nippon Petrochemicals Co., Ltd. (JP) 1989-08-02 EP disclosed
EP-0180771-A1 Method for improving impulse breakdown strength of electrically insulating materials Nippon Petrochemicals Co., Ltd. (JP) 1986-05-14 EP disclosed