Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1557719 | 0.82 | ALDH1A1 (0.46) | ALOX5GABRA1CNR2GABRB2ALDH1A1 | |
| SCHEMBL4907974 | 0.82 | AKT1 (0.57) | AKT1ATMKDM4EALDH1A1CYP1A2 | |
| SCHEMBL7489270 | 0.81 | PKM (0.45) | ALOX5GABRA1CNR2GABRB2ALDH1A1 | |
| SCHEMBL24021272 | 0.78 | ALDH1A1 (0.49) | ALOX5GABRA1CNR2GABRB2ALDH1A1 | |
| SCHEMBL29119944 | 0.78 | TUBB1 (0.48) | AKT1ATMKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL31422450 | 0.77 | GAA (0.60) | ALOX5SMN1; SMN2ALDH1A1POLBPKM | |
| SCHEMBL929750 | 0.77 | MEN1 (0.45) | KDM4ESMN1; SMN2ALDH1A1CYP1A2POLB | |
| SCHEMBL13694250 | 0.76 | AKT1 (0.56) | AKT1ALOX5GABRA1GABRB2ATM | |
| SCHEMBL1332082 | 0.76 | ATM (0.66) | ATMKDM4ESMN1; SMN2ALDH1A1PPARG | |
| SCHEMBL4616323 | 0.76 | BACE1 (0.45) | AKT1ALOX5GABRA1CNR2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879562-A2 | PHENOL DERIVATIVES AND THEIR USE TO MODULATE PKB ACTIVITY | Imperial Innovations Limited (GB) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006097744-A2 | PHENOL DERIVATIVES AND THEIR USE TO MODULATE PKB ACTIVITY | IMPERIAL INNOVATIONS LIMITED (GB) | 2006-09-21 | — | — | WO | disclosed |