Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4065047 | 0.92 | MAOB (0.45) | SLC6A3SLC6A2SLC6A4ALDH1A1HPGD | |
| SCHEMBL4618325 | 0.81 | ALDH1A1 (0.44) | ALDH1A1HPGDMAOBMAPTMEN1 | |
| SCHEMBL4058374 | 0.81 | SIRT1 (0.54) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL4618331 | 0.79 | ALDH1A1 (0.43) | ALDH1A1HPGDMAOBMAPTMEN1 | |
| SCHEMBL4066727 | 0.78 | ABL1 (0.45) | SLC6A3SLC6A4ALDH1A1HPGDMAOB | |
| SCHEMBL4059186 | 0.78 | MAOB (0.43) | ALDH1A1HPGDMAOBMAPTMEN1 | |
| SCHEMBL4060386 | 0.74 | SLC6A2 (0.51) | SLC6A3SLC6A2SLC6A4ALDH1A1HPGD | |
| SCHEMBL4066723 | 0.71 | MAPT (0.45) | SLC6A3SLC6A4ALDH1A1HPGDMAPT | |
| SCHEMBL4068766 | 0.70 | HSD17B10 (0.51) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL4064890 | 0.69 | POLB (0.50) | ALDH1A1MAPTKDM4EPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893596-A2 | BENZOÝB¨FURANE AND BENZOÝB¨THIOPHENE DERIVATIVES | H.Lundbeck A/S (DK) | 2008-03-05 | — | — | EP | disclosed |
| WO-2007023395-A2 | BENZO[B]FURANE AND BENZO[B]THIOPHENE DERIVATIVES | H. LUNDBECK A/S (US) | 2007-03-01 | — | — | WO | disclosed |