Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4618325 | 0.88 | ALDH1A1 (0.44) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL4066727 | 0.87 | ABL1 (0.45) | ALDH1A1HPGDKMT2AMAOBHDAC3 | |
| SCHEMBL4059186 | 0.84 | MAOB (0.43) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL4066723 | 0.80 | MAPT (0.45) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL4065047 | 0.80 | MAOB (0.45) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL4616482 | 0.79 | SLC6A3 (0.41) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL4068766 | 0.78 | HSD17B10 (0.51) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL4064890 | 0.75 | POLB (0.50) | ALDH1A1MAPTCNR2HDAC3HDAC4 | |
| SCHEMBL4058374 | 0.74 | SIRT1 (0.54) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL4436373 | 0.72 | ALDH1A1 (0.56) | ALDH1A1HPGDMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893596-A2 | BENZOÝB¨FURANE AND BENZOÝB¨THIOPHENE DERIVATIVES | H.Lundbeck A/S (DK) | 2008-03-05 | — | — | EP | disclosed |
| WO-2007023395-A2 | BENZO[B]FURANE AND BENZO[B]THIOPHENE DERIVATIVES | H. LUNDBECK A/S (US) | 2007-03-01 | — | — | WO | disclosed |