Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | S100B | P04271 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5420282 | 0.98 | CYP3A4 (0.50) | CYP3A4ALDH1A1TDP1ALOX15HIF1A | |
| SCHEMBL4859720 | 0.90 | ALDH1A1 (0.46) | CYP3A4ALDH1A1TDP1ALOX15HIF1A | |
| SCHEMBL14338947 | 0.84 | ALDH1A1 (0.46) | CYP3A4ALDH1A1TDP1ALOX15HIF1A | |
| SCHEMBL2126641 | 0.80 | CYP3A4 (0.53) | CYP3A4ALDH1A1TDP1ALOX15HIF1A | |
| SCHEMBL6813401 | 0.79 | ALDH1A1 (0.52) | CYP3A4ALDH1A1TDP1ALOX15HIF1A | |
| SCHEMBL2554851 | 0.78 | ALDH1A1 (0.41) | CYP3A4ALDH1A1TDP1ALOX15HIF1A | |
| SCHEMBL2933227 | 0.77 | ALDH1A1 (0.58) | CYP3A4ALDH1A1TDP1ALOX15HIF1A | |
| SCHEMBL6376391 | 0.77 | ALDH1A1 (0.53) | CYP3A4ALDH1A1TDP1ALOX15HIF1A | |
| SCHEMBL6369929 | 0.76 | ALDH1A1 (0.56) | CYP3A4ALDH1A1TDP1ALOX15HIF1A | |
| Hydrochloric Acid SCHEMBL4952474 | 0.76 | ALDH1A1 (0.51) | CYP3A4ALDH1A1TDP1ALOX15HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1739074-B1 | Novel double para-phenylenediamines joined by a branched aliphatic group and use in dyeing | OREAL (FR) | 2008-03-12 | — | — | EP | disclosed |
| EP-1739074-B1 | Novel double para-phenylenediamines joined by a branched aliphatic group and use in dyeing | OREAL (FR) | 2008-03-12 | — | — | EP | disclosed |
| US-20070011828-A1 | Novel double para-phenylenediamines joined by a branched aliphatic group and method of dyeing keratin fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| US-20070011828-A1 | Novel double para-phenylenediamines joined by a branched aliphatic group and method of dyeing keratin fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| EP-1739074-A1 | Novel double para-phenylenediamines joined by a branched aliphatic group and use in dyeing | L'OREAL (FR) | 2007-01-03 | — | — | EP | disclosed |
| EP-1739074-A1 | Novel double para-phenylenediamines joined by a branched aliphatic group and use in dyeing | L'OREAL (FR) | 2007-01-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070011828-A1 | Novel double para-phenylenediamines joined by a branched aliphatic group and method of dyeing keratin fibers | KRT18, CDC73, DSP | CYP3A4 3719/4885ALDH1A1 976/4885TDP1 2217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.