Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.74 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.74 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | P4HB | P07237 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25128778 | 0.86 | KMT2A (0.76) | KMT2APAX8HSD11B1ALDH1A1LMNA | |
| SCHEMBL1951415 | 0.86 | KMT2A (0.76) | KMT2APAX8HSD11B1ALDH1A1LMNA | |
| SCHEMBL28825135 | 0.85 | KMT2A (1.00) | KMT2APAX8HSD11B1ALDH1A1LMNA | |
| SCHEMBL28825174 | 0.85 | KMT2A (1.00) | KMT2APAX8HSD11B1ALDH1A1LMNA | |
| SCHEMBL29275318 | 0.84 | HSD11B1 (0.78) | KMT2APAX8HSD11B1ALDH1A1LMNA | |
| SCHEMBL21541110 | 0.82 | KMT2A (0.70) | KMT2APAX8HSD11B1ALDH1A1LMNA | |
| SCHEMBL12264849 | 0.82 | KMT2A (0.70) | KMT2APAX8HSD11B1ALDH1A1LMNA | |
| SCHEMBL908478 | 0.81 | PKM (0.75) | KMT2APAX8HSD11B1ALDH1A1LMNA | |
| SCHEMBL20634038 | 0.80 | KMT2A (0.67) | KMT2APAX8HSD11B1ALDH1A1LMNA | |
| SCHEMBL20633923 | 0.79 | KMT2A (0.65) | KMT2APAX8HSD11B1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893741-A1 | CELL-BASED MICROARRAYS, AND METHODS FOR THEIR PREPARATION AND USE | Beckman Coulter, Inc. (US) | 2008-03-05 | — | — | EP | disclosed |
| WO-2007001817-A1 | CELL-BASED MICROARRAYS, AND METHODS FOR THEIR PREPARATION AND USE | BECKMAN COULTER, INC. (US) | 2007-01-04 | — | — | WO | disclosed |