Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.73 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.68 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30008266 | 0.87 | HSD11B1 (0.74) | PKMKMT2APAX8HSD11B1ALDH1A1 | |
| SCHEMBL25128778 | 0.82 | KMT2A (0.76) | PKMKMT2APAX8HSD11B1ALDH1A1 | |
| SCHEMBL1951415 | 0.82 | KMT2A (0.76) | KMT2APAX8HSD11B1ALDH1A1LMNA | |
| SCHEMBL28825174 | 0.81 | KMT2A (1.00) | KMT2APAX8HSD11B1ALDH1A1LMNA | |
| SCHEMBL4617628 | 0.81 | KMT2A (0.74) | KMT2APAX8HSD11B1ALDH1A1LMNA | |
| SCHEMBL28825135 | 0.81 | KMT2A (1.00) | KMT2APAX8HSD11B1ALDH1A1LMNA | |
| SCHEMBL29275318 | 0.81 | HSD11B1 (0.78) | KMT2APAX8HSD11B1ALDH1A1LMNA | |
| SCHEMBL12264849 | 0.79 | KMT2A (0.70) | PKMKMT2APAX8HSD11B1ALDH1A1 | |
| SCHEMBL21541110 | 0.79 | KMT2A (0.70) | PKMKMT2APAX8HSD11B1ALDH1A1 | |
| SCHEMBL7861808 | 0.77 | HTT (0.57) | PKMKMT2AHSD11B1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8816051-B2 | Conjugated biological molecules and their preparation | POLYTHERICS LIMITED (GB) | 2014-08-26 | — | — | US | disclosed |
| US-20110182855-A1 | CONJUGATED BIOLOGICAL MOLECULES AND THEIR PREPARATION | POLYTHERICS LIMITED (GB) | 2011-07-28 | — | — | US | disclosed |
| EP-2277550-A1 | Conjugated biological molecules and their preparation | Polytherics Limited (GB) | 2011-01-26 | — | — | EP | disclosed |
| US-20060210526-A1 | polyoxyethylene glycol-protein conjugate linked via linking group | ABZENA (CAMBRIDGE) LIMITED (GB) | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110182855-A1 | CONJUGATED BIOLOGICAL MOLECULES AND THEIR PREPARATION | F13B, ZYX, F13A1 | PKM 2623/4885KMT2A 4253/4885PAX8 1683/4885 |
| US-20060210526-A1 | polyoxyethylene glycol-protein conjugate linked via linking group | F13A1, F13B, SSB | PKM 3131/4885KMT2A 4148/4885PAX8 2398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.