SCHEMBL4617700

SCHEMBL4617700

CC(C)(C)OC(=O)[C@](N)(CCCCN)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ODC1 P11926 2/20 0.37
ARG1 P05089 4/20 0.35
ARG2 P78540 4/20 0.35
LMNA P02545 2/20 0.35
BLM P54132 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
RAB9A P51151 1/20 0.35
PMP22 Q01453 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
DGAT1 O75907 1/20 0.33
ACACB O00763 1/20 0.33
ACACA Q13085 1/20 0.33
CYP2D6 P10635 1/20 0.32
NFKB1 P19838 1/20 0.32
FDPS P14324 2/20 0.32
NPSR1 Q6W5P4 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PLG P00747 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28914719 1.00 ODC1 (0.37) ODC1ARG1ARG2LMNABLM
SCHEMBL4617707 1.00 ODC1 (0.37) ODC1ARG1ARG2LMNABLM
SCHEMBL2270879 0.95 ODC1 (0.42) ODC1ARG1ARG2LMNABLM
SCHEMBL9016090 0.95 ODC1 (0.42) ODC1ARG1ARG2LMNABLM
SCHEMBL2270874 0.95 ODC1 (0.42) ODC1ARG1ARG2LMNABLM
SCHEMBL7802855 0.91 DGAT1 (0.36) ODC1ARG1ARG2LMNABLM
SCHEMBL9196272 0.89 PAOX (0.36) ODC1LMNADGAT1FDPSMEN1
SCHEMBL587833 0.89 PAOX (0.36) ODC1LMNADGAT1FDPSMEN1
SCHEMBL20496960 0.89 PAOX (0.36) ODC1LMNADGAT1FDPSMEN1
SCHEMBL7705520 0.87 DGAT1 (0.41) ODC1ARG1ARG2LMNABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118359572-B Non-natural amino acid based on thiocoumarin, and preparation method and application thereof 北京大学深圳研究生院 2024-12-13 CN claimed
CN-118359572-A Non-natural amino acid based on thiocoumarin, and preparation method and application thereof 北京大学深圳研究生院 2024-07-19 CN claimed
CN-111280244-B Fresh-keeping agent for salmon and fresh-keeping method thereof 渤海大学 2023-07-11 CN claimed
CN-118359572-B Non-natural amino acid based on thiocoumarin, and preparation method and application thereof 北京大学深圳研究生院 2024-12-13 CN disclosed
CN-118359572-A Non-natural amino acid based on thiocoumarin, and preparation method and application thereof 北京大学深圳研究生院 2024-07-19 CN disclosed
CN-117624207-A Glucose-sensitive albumin binding derivatives 诺和诺德股份有限公司 2024-03-01 CN disclosed
CN-113929740-B Amphiphilic polypeptide and preparation method and application thereof 中国科学技术大学 2024-01-16 CN disclosed
CN-111315751-B Glucose-sensitive albumin binding derivatives 诺和诺德股份有限公司 2023-12-12 CN disclosed
CN-111562720-B Photo-sensitized chemically amplified resist material, pattern forming method, semiconductor device, mask for lithography, and template for nanoimprint 东京毅力科创株式会社 2023-09-29 CN disclosed
CN-111280244-B Fresh-keeping agent for salmon and fresh-keeping method thereof 渤海大学 2023-07-11 CN disclosed
CN-115850435-A Mutant of non-natural amino acid substituted IL-15, conjugate and application 惠大首业(北京)投资有限公司 2023-03-28 CN disclosed
EP-0618192-B1 Homobidental, trifunctional maleimide linkers and their application in immunologically active conjugates BOEHRINGER MANNHEIM GMBH (DE) 1998-09-16 EP disclosed
US-5686251-A Naphthyridinium derivatives NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) 1997-11-11 US disclosed
US-5601824-A Homobidental, trifunctional linkers used in immunologically active conjugates BOEHRINGER MANNHEIM GMBH (DE) 1997-02-11 US disclosed
US-5519142-A Homobidental, trifunctional linkers, method for their preparation and use in immunologically active conjugates BOEHRINGER MANNHEIM GMBH (DE) 1996-05-21 US disclosed
US-5514559-A STORAGE STABILITY BOEHRINGER MANNHEIM GMBH (DE) 1996-05-07 US disclosed
EP-0695750-A1 Naphthyridinium derivative, method for its production; antibody against said derivative and the use of said antibody NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) 1996-02-07 EP disclosed
EP-0618192-A1 Homobidental, trifunctional mazeimide linkers and their application in immunologically active conjugates Roche Diagnostics GmbH (DE) 1994-10-05 EP disclosed
EP-0618231-A1 Immunologically active conjugates and a method for their preparation Roche Diagnostics GmbH (DE) 1994-10-05 EP disclosed
US-4778752-A MONOCLONAL ANTIBODIES BINDING REDUCED GLYCOSYLATED PROTEINS; BLOOD ANALYSIS OF DIABETICS SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) 1988-10-18 US disclosed