SCHEMBL7705520

SCHEMBL7705520

CC(C)(C)OC(=O)C(N)(CCN)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.41
GGT1 P19440 1/20 0.33
ODC1 P11926 2/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32
CTSS P25774 1/20 0.31
CTSK P43235 1/20 0.31
CA12 O43570 2/20 0.31
CA14 Q9ULX7 2/20 0.31
CA2 P00918 1/20 0.31
ARG1 P05089 1/20 0.31
ARG2 P78540 1/20 0.31
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1066048 1.00 DGAT1 (0.41) DGAT1GGT1ODC1MEN1GAA
SCHEMBL569250 0.90 DGAT1 (0.45) DGAT1MEN1GAAKMT2ACA12
SCHEMBL2270874 0.89 ODC1 (0.42) DGAT1GGT1ODC1MEN1GAA
SCHEMBL2270879 0.89 ODC1 (0.42) DGAT1GGT1ODC1MEN1GAA
SCHEMBL9016090 0.89 ODC1 (0.42) DGAT1GGT1ODC1MEN1GAA
SCHEMBL4617700 0.87 ODC1 (0.37) DGAT1GGT1ODC1MEN1KMT2A
SCHEMBL28914719 0.87 ODC1 (0.37) DGAT1GGT1ODC1MEN1KMT2A
SCHEMBL4617707 0.87 ODC1 (0.37) DGAT1GGT1ODC1MEN1KMT2A
SCHEMBL6372947 0.85 DGAT1 (0.36) DGAT1GGT1MEN1KMT2ACTSS
SCHEMBL27465368 0.85 DGAT1 (0.36) DGAT1GGT1ARG1ARG2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116874803-A Antibacterial dendritic polyester polymer and preparation method and application thereof 清华大学深圳国际研究生院 2023-10-13 CN claimed
CN-116874803-A Antibacterial dendritic polyester polymer and preparation method and application thereof 清华大学深圳国际研究生院 2023-10-13 CN disclosed
CN-116829523-A Phenol derivative, crystal form and preparation method thereof 天地恒一制药股份有限公司 2023-09-29 CN disclosed
EP-3094641-A1 NOVEL LIGANDS FOR PREVENTION OF NEUROTOXICITY OF THE ALZHEIMER'S DISEASE RELATED AMYLOID-BETA PEPTIDE Alphabeta AB (SE) 2016-11-23 EP disclosed
CN-104894295-A Novel virus double-fluorescence labeling method based on nucleic acid and protein biosynthesis BEIJING INST TECHNOLOGY 2015-09-09 CN disclosed
WO-2015107170-A1 NOVEL LIGANDS FOR PREVENTION OF NEUROTOXICITY OF THE ALZHEIMER'S DISEASE RELATED AMYLOID-BETA PEPTIDE ALPHABETA AB (SE) 2015-07-23 WO disclosed
CN-104651085-A Detergent for lead-polluted building wastes YANTAI SHUNLONG CHEMICAL ENGINEERING CO LTD 2015-05-27 CN disclosed
CN-104557861-A Hcv protease inhibitors and uses thereof AVILA THERAPEUTICS INC 2015-04-29 CN disclosed
CN-101951770-B Hcv protease inhibitors and uses thereof AVILA THERAPEUTICS INC 2014-12-31 CN disclosed
US-6358921-B1 CYCLIC POLYPEPTIDE WITH LOW HEMOLYTIC ACTIVITY; KILLING FUNGI, MYCOPLAMA, GRAMPOSITIVE AND GRAMNEGATIVE BACTERIA; SIDE EFFECT REDUCTION PENCE, INC. (CA) 2002-03-19 US disclosed
WO-2001000656-A2 NOVEL INDAZOLE PEPTIDOMIMETICS AS THROMBIN RECEPTOR ANTAGONISTS ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2001-01-04 WO disclosed