Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4617948 | 1.00 | CYP1A2 (0.52) | CYP1A2AHRNFE2L2PPARGALOX5 | |
| SCHEMBL28760348 | 0.82 | CA12 (0.40) | NFE2L2PPARGPTGES2HDAC2HDAC3 | |
| SCHEMBL4618879 | 0.81 | SMN1; SMN2 (0.44) | CYP1A2MAOBHDAC1HDAC8CXCL12 | |
| SCHEMBL950722 | 0.80 | HSD17B10 (0.52) | CYP1A2AHRNFE2L2PPARGALOX5 | |
| SCHEMBL950718 | 0.80 | HSD17B10 (0.52) | CYP1A2AHRNFE2L2PPARGALOX5 | |
| SCHEMBL2298614 | 0.80 | APP (0.52) | CYP1A2NFE2L2PPARGALOX5PTGS1 | |
| SCHEMBL2298611 | 0.80 | APP (0.52) | CYP1A2NFE2L2PPARGALOX5PTGS1 | |
| SCHEMBL2130152 | 0.78 | NFE2L2 (0.53) | CYP1A2AHRNFE2L2PPARGALOX5 | |
| SCHEMBL2173890 | 0.78 | LMNA (0.53) | NFE2L2PPARGALOX5PTGS1PTGS2 | |
| SCHEMBL29496 | 0.78 | TDP1 (0.57) | CYP1A2NFE2L2PPARGMAOBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1684744-A4 | PYRROLIDINE AND PIPERIDINE DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2008-12-17 | — | — | EP | claimed |
| US-7169795-B2 | Sulfonylaminovalerolactams and derivatives thereof as factor Xa inhibitors | BRISTOL MYERS SQUIBB COMPANY (US) | 2007-01-30 | — | — | US | claimed |
| EP-1684744-A2 | PYRROLIDINE AND PIPERIDINE DERIVATIVES AS FACTOR XA INHIBITORS | Bristol-Myers Squibb Company (US) | 2006-08-02 | — | — | EP | claimed |
| US-20050119266-A1 | Pyrrolidine and piperidine derivatives as factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2005-06-02 | — | — | US | claimed |
| US-20050096309-A1 | Sulfonylaminovalerolactams and derivatives thereof as factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2005-05-05 | — | — | US | claimed |
| WO-2005032472-A2 | PYRROLIDINE AND PIPERIDINE DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-04-14 | — | — | WO | claimed |
| US-4263201-A | ORGANIC ACID METAL SALT, HALOGEN COMPOUND | GENERAL ELECTRIC COMPANY (US) | 1981-04-21 | — | — | US | claimed |
| US-12185579-B2 | Organic light emitting diode and manufacturing method thereof, and display panel | WUHAN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) | 2024-12-31 | — | — | US | disclosed |
| US-20240023370-A1 | ORGANIC LIGHT EMITTING DIODE AND MANUFACTURING METHOD THEREOF, AND DISPLAY PANEL | WUHAN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) | 2024-01-18 | — | — | US | disclosed |
| WO-2023272815-A1 | ORGANIC LIGHT-EMITTING DIODE, PREPARATION METHOD THEREFOR, AND DISPLAY PANEL | 武汉华星光电技术有限公司 | 2023-01-05 | — | — | WO | disclosed |
| CN-113471374-A | Organic light emitting diode, preparation method thereof and display panel | 武汉华星光电技术有限公司 | 2021-10-01 | — | — | CN | disclosed |
| EP-1684744-A4 | PYRROLIDINE AND PIPERIDINE DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2008-12-17 | — | — | EP | disclosed |
| CN-101268042-A | Styryl sulfonamides, their preparation and use as pharmaceutical agents | HOFFMANN LA ROCHE (CH) | 2008-09-17 | — | — | CN | disclosed |
| EP-1667635-A2 | SULFONYLAMINOVALEROLACTAMS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | Bristol-Myers Squibb Company (US) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005048922-A2 | SULFONYLAMINOVALEROLACTAMS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-06-02 | — | — | WO | disclosed |
| US-20050119266-A1 | Pyrrolidine and piperidine derivatives as factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2005-06-02 | — | — | US | disclosed |
| US-20050096309-A1 | Sulfonylaminovalerolactams and derivatives thereof as factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2005-05-05 | — | — | US | disclosed |
| WO-2005032472-A2 | PYRROLIDINE AND PIPERIDINE DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-04-14 | — | — | WO | disclosed |
| US-4075164-A | AROMATIC CARBONATE POLYMER | GENERAL ELECTRIC COMPANY (US) | 1978-02-21 | — | — | US | disclosed |
| US-3940366-A | AROMATIC METAL SULFONATE | GENERAL ELECTRIC COMPANY (US) | 1976-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119266-A1 | Pyrrolidine and piperidine derivatives as factor Xa inhibitors | PEPD, SERPINE1, PRSS1 | CYP1A2 3037/4885AHR 4474/4885NFE2L2 4151/4885 |
| US-20050096309-A1 | Sulfonylaminovalerolactams and derivatives thereof as factor Xa inhibitors | TFPI, F12, F5 | CYP1A2 2107/4885AHR 3640/4885NFE2L2 4570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.