Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1134032 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL1278919 | 0.91 | ALOX15 (0.46) | GAAALOX15MGAMSIMGAM2 | |
| Hydrochloric Acid SCHEMBL4880200 | 0.88 | MMP8 (0.44) | GAAALOX15MGAMSIMGAM2 | |
| SCHEMBL4270735 | 0.81 | ALOX15 (0.38) | ALOX15CYP4F2CYP4A11ALDH1A1PKM | |
| Hydrochloric Acid SCHEMBL27418611 | 0.80 | ALOX15 (0.41) | GAAALOX15MGAMSIMGAM2 | |
| SCHEMBL27516860 | 0.80 | GAA (0.41) | GAAALOX15MGAMSIMGAM2 | |
| Hydrochloric Acid SCHEMBL27723750 | 0.80 | ALOX15 (0.41) | GAAALOX15MGAMSIMGAM2 | |
| SCHEMBL8632493 | 0.78 | — | — | |
| SCHEMBL22747722 | 0.78 | ALOX15 (0.48) | GAAALOX15MGAMSIMGAM2 | |
| Hydrochloric Acid SCHEMBL10531755 | 0.76 | ALOX15 (0.46) | GAAALOX15MGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888063-A1 | ANTIFUNGAL AGENTS | F2G Ltd. (GB) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006123145-A1 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2006-11-23 | — | — | WO | disclosed |