Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 17/20 | 0.44 |
| ▸ | CNR1 | P21554 | 4/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6101911 | 0.92 | PIK3CD (0.39) | CNR2CNR1NAMPT | |
| SCHEMBL6102825 | 0.88 | SFRP1 (0.37) | CNR2 | |
| SCHEMBL4617093 | 0.85 | CNR2 (0.45) | CNR2CNR1NAMPTHTR1ADRD2 | |
| SCHEMBL4616909 | 0.84 | CNR2 (0.41) | CNR2NAMPTHTR1ADRD2HTR7 | |
| SCHEMBL4617752 | 0.84 | HTR1A (0.47) | CNR2CNR1HTR1ADRD2HTR7 | |
| SCHEMBL4638042 | 0.81 | CNR2 (0.53) | CNR2 | |
| SCHEMBL4617625 | 0.78 | PIK3CD (0.42) | CNR2CNR1 | |
| SCHEMBL4618266 | 0.78 | KMT2A (0.48) | CNR2HTR1ADRD2HTR7HTR6 | |
| SCHEMBL4637629 | 0.77 | PIK3CD (0.41) | CNR2HTR1ADRD2HTR7HTR6 | |
| SCHEMBL4616319 | 0.76 | PDE4A (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879859-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | Wyeth a Corporation of the State of Delaware (US) | 2008-01-23 | — | — | EP | claimed |
| US-20060276464-A1 | Diarylsulfone sulfonamides and use thereof | WYETH (US) | 2006-12-07 | — | — | US | claimed |
| WO-2006124875-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | WYETH (US) | 2006-11-23 | — | — | WO | claimed |
| US-20060276464-A1 | Diarylsulfone sulfonamides and use thereof | WYETH (US) | 2006-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276464-A1 | Diarylsulfone sulfonamides and use thereof | SFRP1, SOS1, FZD7 | CNR2 3896/4885CNR1 2978/4885NAMPT 3852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.