Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4620376 | 0.93 | KMT2A (0.40) | AGTR2SMN1; SMN2LMNAMAPTMEN1 | |
| SCHEMBL3176403 | 0.77 | AGTR2 (0.52) | AGTR2MEN1KMT2APDE3AKDM4E | |
| SCHEMBL21125120 | 0.77 | TSHR (0.47) | AGTR2SMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL7461684 | 0.76 | KDM4E (0.43) | NPSR1AGTR2ALDH1A1LMNATDP1 | |
| SCHEMBL9088018 | 0.74 | AGTR2 (0.55) | AGTR2MEN1KMT2APDE3AKDM4E | |
| SCHEMBL8265591 | 0.72 | AGTR1 (0.64) | AGTR2PDE3AABCB11EGFRERBB2 | |
| SCHEMBL22533796 | 0.72 | AGTR2 (0.51) | AGTR2ALDH1A1MEN1KMT2APDE3A | |
| SCHEMBL17998734 | 0.70 | AGTR2 (0.57) | AGTR2MEN1KMT2APDE3AKDM4E | |
| SCHEMBL8562283 | 0.69 | AGTR2 (0.58) | AGTR2MEN1KMT2APDE3AKDM4E | |
| SCHEMBL8562281 | 0.68 | AGTR2 (0.58) | AGTR2MEN1KMT2APDE3AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891053-A1 | METHOD FOR OBTAINING BENZIMIDAZOLE DERIVATIVES AND INTERMEDIATES THEREOF | Quimica Sintetica, S.A. (ES) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006134078-A1 | METHOD FOR OBTAINING BENZIMIDAZOLE DERIVATIVES AND INTERMEDIATES THEREOF | QUIMICA SINTETICA, S.A. (ES) | 2006-12-21 | — | — | WO | disclosed |