Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4619422 | 0.93 | RAB9A (0.40) | KMT2ACYP3A4CYP2C9MEN1TP53 | |
| SCHEMBL3176403 | 0.84 | AGTR2 (0.52) | KMT2ASLC6A3CYP3A4CYP2C9MEN1 | |
| SCHEMBL8265591 | 0.73 | AGTR1 (0.64) | CYP3A4CYP2C9ABCB11EGFRERBB2 | |
| SCHEMBL22533557 | 0.72 | AGTR2 (0.51) | KMT2ASLC6A3CYP3A4CYP2C9MEN1 | |
| SCHEMBL3977106 | 0.72 | AGTR2 (0.62) | KMT2ASLC6A3CYP3A4CYP2C9MEN1 | |
| SCHEMBL7461684 | 0.71 | KDM4E (0.43) | CYP3A4CYP2C9AGTR1PPARGAGTR2 | |
| SCHEMBL21167865 | 0.70 | AGTR2 (0.57) | KMT2ASLC6A3CYP3A4CYP2C9MEN1 | |
| SCHEMBL12476143 | 0.69 | AGTR2 (0.58) | KMT2ASLC6A3CYP3A4CYP2C9MEN1 | |
| SCHEMBL21168140 | 0.69 | AGTR2 (0.59) | KMT2ASLC6A3CYP3A4CYP2C9MEN1 | |
| SCHEMBL30206864 | 0.69 | PPARG (0.59) | KMT2ASLC6A3CYP3A4CYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891053-A1 | METHOD FOR OBTAINING BENZIMIDAZOLE DERIVATIVES AND INTERMEDIATES THEREOF | Quimica Sintetica, S.A. (ES) | 2008-02-27 | — | — | EP | claimed |
| WO-2006134078-A1 | METHOD FOR OBTAINING BENZIMIDAZOLE DERIVATIVES AND INTERMEDIATES THEREOF | QUIMICA SINTETICA, S.A. (ES) | 2006-12-21 | — | — | WO | claimed |