Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.45 |
| ▸ | G6PD | P11413 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8707338 | 0.78 | CYP19A1 (0.46) | CYP19A1G6PDMEN1LMNASHBG | |
| SCHEMBL4619435 | 0.74 | CYP19A1 (0.40) | CYP19A1G6PDMEN1LMNASHBG | |
| SCHEMBL5310140 | 0.72 | CYP19A1 (0.43) | CYP19A1SHBG | |
| SCHEMBL28141770 | 0.71 | CYP19A1 (0.48) | CYP19A1G6PDMEN1LMNASHBG | |
| SCHEMBL23155091 | 0.70 | SHBG (0.64) | G6PDMEN1LMNASHBGSERPINA6 | |
| SCHEMBL13076860 | 0.70 | SHBG (0.64) | G6PDMEN1LMNASHBGSERPINA6 | |
| SCHEMBL3366382 | 0.70 | SHBG (0.64) | G6PDMEN1LMNASHBGSERPINA6 | |
| SCHEMBL12310691 | 0.70 | SHBG (0.64) | G6PDMEN1LMNASHBGSERPINA6 | |
| SCHEMBL11970666 | 0.70 | SHBG (0.64) | G6PDMEN1LMNASHBGSERPINA6 | |
| SCHEMBL14149814 | 0.70 | SHBG (0.64) | G6PDMEN1LMNASHBGSERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1890679-A2 | STEROID KIT AND FOAMABLE COMPOSITION AND USES THEREOF | Foamix Ltd. (IL) | 2008-02-27 | — | — | EP | disclosed |
| WO-2007012977-A2 | STEROID KIT AND FOAMABLE COMPOSITION AND USES THEREOF | FOAMIX LTD (US) | 2007-02-01 | — | — | WO | disclosed |