Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3003760 | 0.82 | MAPT (0.57) | MAPTGAATSHRMAPK1HTT | |
| SCHEMBL3951418 | 0.81 | GABRA1 (0.56) | MAPTGAATSHRMAPK1HTT | |
| SCHEMBL885029 | 0.81 | HSD17B10 (0.57) | ALDH1A1TAAR1ADRA1AIDO1 | |
| SCHEMBL30229484 | 0.81 | HSD17B10 (0.57) | ALDH1A1TAAR1ADRA1AIDO1 | |
| SCHEMBL30536248 | 0.81 | ALDH1A1 (0.52) | GAATSHRKDM4EALDH1A1USP2 | |
| SCHEMBL2689127 | 0.81 | ALDH1A1 (0.52) | GAATSHRKDM4EALDH1A1USP2 | |
| SCHEMBL12476008 | 0.81 | ACHE (0.50) | MAPTGAATSHRMAPK1KDM4E | |
| SCHEMBL929750 | 0.80 | MEN1 (0.45) | MAPTKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL696593 | 0.80 | BACE1 (0.47) | MAPTGAAHTTKDM4EALDH1A1 | |
| SCHEMBL1821904 | 0.80 | KDM4E (0.51) | MAPTGAATSHRMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888063-A1 | ANTIFUNGAL AGENTS | F2G Ltd. (GB) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006123145-A1 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2006-11-23 | — | — | WO | disclosed |
| WO-2001046170-A1 | AMIDINE DERIVATIVES WHICH ARE INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRAZENECA AB (SE) | 2001-06-28 | — | — | WO | disclosed |
| WO-2001046171-A1 | AMIDINE DERIVATIVES WHICH ARE INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRAZENECA AB (SE) | 2001-06-28 | — | — | WO | disclosed |
| EP-0866790-A1 | 3-BENZYLAMINOPYRROLIDINES AND -PIPERIDINES AS TACHYKININ RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME LTD. (GB) | 1998-09-30 | — | — | EP | disclosed |
| WO-1997021702-A1 | 3-BENZYLAMINOPYRROLIDINES AND -PIPERIDINES AS TACHYKININ RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME LIMITED (GB) | 1997-06-19 | — | — | WO | disclosed |