SCHEMBL461952

SCHEMBL461952

C=CCOC[C@H](COP(=O)(O)OCCN)OCC=C

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PLA2G2C Q5R387 1/20 0.45
LPAR1 Q92633 2/20 0.34
LPAR3 Q9UBY5 2/20 0.34
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
P2RY10 O00398 1/20 0.32
PLA2G2D Q9UNK4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9237355 0.87 PLA2G2C (0.37) PLA2G2CLPAR1LPAR3CA1CA2
SCHEMBL22778250 0.86 LPAR1 (0.43) PLA2G2CLPAR1LPAR3CA1CA2
SCHEMBL22778183 0.85 LPAR1 (0.45) PLA2G2CLPAR1LPAR3P2RY10
SCHEMBL22778166 0.83 LPAR1 (0.38) PLA2G2CLPAR1LPAR3CA1CA2
SCHEMBL22778213 0.81 PLA2G2A (0.38) LPAR1LPAR3CA1CA2CA7
SCHEMBL23130705 0.81 P2RY10 (0.45) P2RY10
SCHEMBL28528617 0.81 CA1 (0.38) LPAR1LPAR3CA1CA2CA7
SCHEMBL28206699 0.81 LPAR3 (0.46) LPAR1LPAR3CA1CA2CA7
SCHEMBL28002680 0.81 LPAR3 (0.46) LPAR1LPAR3CA1CA2CA7
Methyl Alcohol SCHEMBL28536635 0.78 LPAR3 (0.48) LPAR1LPAR3CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3982932-A1 COMPOSITIONS AND METHODS FOR BIOLOGICAL DELIVERY VEHICLES Dnalite Therapeutics, Inc. (US) 2022-04-20 EP claimed
CN-114286671-A Compositions and methods for biological delivery vehicles DNALite治疗学公司 2022-04-05 CN claimed
US-10961197-B2 Metal chelators for imaging, therapeutics, and bioanalysis THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2021-03-30 US claimed
WO-2020252375-A1 COMPOSITIONS AND METHODS FOR BIOLOGICAL DELIVERY VEHICLES DNALITE THERAPEUTICS, INC. (US) 2020-12-17 WO claimed
EP-1771206-B1 LIPIDS, LIPID COMPLEXES AND USE THEREOF SILENCE THERAPEUTICS GMBH (DE) 2018-04-11 EP claimed
US-9486538-B2 Lipids, lipid complexes and use thereof SILENCE THERAPEUTICS GMBH (DE) 2016-11-08 US claimed
EP-2992875-A1 LIPOPLEX FORMULATIONS FOR SPECIFIC DELIVERY TO VASCULAR ENDOTHELIUM Silence Therapeutics GmbH (DE) 2016-03-09 EP claimed
CN-102940891-B Lipid, lipid complex and application thereof SILENCE THERAPEUTICS AG (DE) 2016-02-24 CN claimed
US-20150359906-A1 LIPIDS, LIPID COMPLEXES AND USE THEREOF SILENCE THERAPEUTICS AG (DE) 2015-12-17 US claimed
EP-1830888-B1 LIPID COMPLEXES COATED WITH PEG AND THEIR USE SILENCE THERAPEUTICS GMBH (DE) 2015-08-05 EP claimed
US-8852472-B2 Coated lipid complexes and their use SILENCE THERAPEUTICS GMBH (DE) 2014-10-07 US claimed
US-8357722-B2 Lipids, lipid complexes and use thereof Silence Therpeutics AG (DE) 2013-01-22 US claimed
US-20120065138-A1 LIPIDS, LIPID COMPLEXES AND USE THEREOF SILENCE THERAPEUTICS AG (DE) 2012-03-15 US claimed
US-20100062967-A1 COATED LIPID COMPLEXES AND THEIR USE SILENCE THERAPEUTICS AG (DE) 2010-03-11 US claimed
US-20080274116-A1 Lipids, Lipid Complexes and Use Thereof SILENCE THERAPEUTICS AG (DE) 2008-11-06 US claimed
JP-2007536324-A 2007-12-13 JP claimed
EP-1771206-A2 LIPIDS, LIPID COMPLEXES AND USE THEREOF atugen AG (DE) 2007-04-11 EP claimed
WO-2005105152-A2 LIPIDS, LIPID COMPLEXES AND USE THEREOF ATUGEN AG (DE) 2005-11-10 WO claimed
EP-3500671-B1 METHOD OF SELECTING TARGET SEQUENCES FOR THE DESIGN OF GUIDE RNAS BROAD INST INC (US) 2024-07-10 EP disclosed
WO-2005105152-A2 LIPIDS, LIPID COMPLEXES AND USE THEREOF ATUGEN AG (DE) 2005-11-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120065138-A1 LIPIDS, LIPID COMPLEXES AND USE THEREOF MGLL, LIPA, SGMS1 PLA2G2C 470/4885LPAR1 34/4885LPAR3 39/4885
US-20100062967-A1 COATED LIPID COMPLEXES AND THEIR USE HDLBP, NR1H3, CETP PLA2G2C 326/4885LPAR1 69/4885LPAR3 108/4885
US-20150359906-A1 LIPIDS, LIPID COMPLEXES AND USE THEREOF MGLL, LIPA, LIPC PLA2G2C 245/4885LPAR1 41/4885LPAR3 44/4885
US-10961197-B2 Metal chelators for imaging, therapeutics, and bioanalysis TBCA, SLC39A3, TBL3 PLA2G2C 3285/4885LPAR1 4015/4885LPAR3 3211/4885
US-20080274116-A1 Lipids, Lipid Complexes and Use Thereof MGLL, LIPA, SGMS1 PLA2G2C 523/4885LPAR1 32/4885LPAR3 39/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.