Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.53 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7657058 | 0.98 | P4HTM (0.54) | P4HTMPIM2ESR1ALDH1A1MAPT | |
| SCHEMBL7657066 | 0.98 | P4HTM (0.54) | P4HTMPIM2ESR1ALDH1A1MAPT | |
| SCHEMBL7482002 | 0.86 | PIM2 (0.54) | P4HTMPIM2ESR1ALDH1A1MAPT | |
| SCHEMBL29551688 | 0.86 | PIM2 (0.54) | P4HTMPIM2ESR1ALDH1A1MAPT | |
| SCHEMBL3786488 | 0.86 | PIM2 (0.54) | P4HTMPIM2ESR1ALDH1A1MAPT | |
| SCHEMBL3786486 | 0.86 | PIM2 (0.54) | P4HTMPIM2ESR1ALDH1A1MAPT | |
| SCHEMBL7482012 | 0.86 | PIM2 (0.54) | P4HTMPIM2ESR1ALDH1A1MAPT | |
| SCHEMBL16789345 | 0.85 | PTGS2 (0.49) | P4HTMPIM2ALDH1A1MAPTLMNA | |
| SCHEMBL4622159 | 0.83 | CA12 (0.47) | ALDH1A1MAPTLMNAALOX12NPSR1 | |
| SCHEMBL3683823 | 0.81 | CA12 (0.51) | ESR1ALDH1A1MAPTLMNAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1882687-A1 | Heterocyclic compounds useful as vanilloid receptor antagonists and pharmaceutical compositions containing the same | Amorepacific Corporation (KR) | 2008-01-30 | — | — | EP | disclosed |