Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.57 |
| ▸ | PTGES | O14684 | 2/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.54 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5599785 | 0.91 | ABCG2 (0.59) | PTPN1ABCG2PTGESABCB1TNFRSF1A | |
| SCHEMBL4620096 | 0.86 | ABCG2 (0.74) | ABCG2ABCB1TNFRSF1AMAOAMAOB | |
| SCHEMBL30428796 | 0.86 | ABCG2 (0.74) | ABCG2ABCB1TNFRSF1AMAOAMAOB | |
| SCHEMBL4620101 | 0.86 | ABCG2 (0.74) | ABCG2ABCB1TNFRSF1AMAOAMAOB | |
| SCHEMBL5599401 | 0.84 | DPP4 (0.67) | ABCG2ABCB1TNFRSF1AMAOAMAOB | |
| SCHEMBL14606162 | 0.78 | MAOB (0.74) | ABCG2PTGESALOX5MAOAMAOB | |
| SCHEMBL16692664 | 0.76 | TSHR (0.66) | PTGES | |
| SCHEMBL9368102 | 0.75 | MAPT (0.63) | PTPN1ALOX5MAOBNR1H4 | |
| SCHEMBL9368112 | 0.75 | MAPT (0.63) | PTPN1ALOX5MAOBNR1H4 | |
| SCHEMBL18010157 | 0.75 | PTGES (0.62) | PTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764363-A2 | SUBSTITUTED ACETOPHENONEDERIVATIVES | Riemser Arzneimittel AG (DE) | 2007-03-21 | — | — | EP | claimed |
| EP-1764363-A2 | SUBSTITUTED ACETOPHENONEDERIVATIVES | Riemser Arzneimittel AG (DE) | 2007-03-21 | — | — | EP | disclosed |